When does research become answers?

Touching the lives of millions of people everywhere. Reaching beyond the ordinary to make an impact on something greater than the bottom line. Playing a key role in some of the most critical issues facing healthcare today.

We are Pfizer Global Research & Development (PGRD), the largest pharmaceutical R&D organization in the world. As Pfizer’s visionary discovery and development division, innovation shapes our strategy, defines our purpose and governs every facet of our operations - from the research and development that leads to pharmaceutical breakthroughs to the way we respond to the changing marketplace.

Our emphasis on innovation has enabled us to bring to market a wide range of outstanding medicines, such as Lipitor® (atorvastatin calcium), Zithromax® (azithromycin), Viracept® (nelfinavir mesylate), Zoloft® (sertraline hydrochloride), Viagra® (sildenafil citrate), and our newest smoking cessation medicine, Chantix® (varenicline). But we recognize that there is much, much more work to be done, and we look forward to conquering the challenges facing global healthcare. Today, our research pipeline spans many therapeutic areas and research projects and we’re committed to bringing even more miracles to the marketplace. Here, we imagine that our world can be a healthier and happier place for all.

We Currently Have The Following Opportunity:

Computational Chemist (R5-R7)

The successful candidate will be expected to build and implement computational strategies to influence the design strategy of drug discovery projects to improve potency, selectivity, physical properties, and ADME profiles. Candidates with experience in  ligand based design, structure based drug design, statistical modeling and/or chemoinformatics are preferred. In this role, you will use structure-based design to guide decision-making; triage HTS data in order to identify the most promising lead matter; conduct virtual screens both to identify and optimize chemical matter; use chemoinformatics to help highlight and drive the most critical issues that face project teams; routinely present your work as a critical component of helping to guide the Discovery process; and develop partnerships with others in order to drive successful drug discovery outcomes.

Candidates must have a Ph.D. with a strong record of experience in computational chemistry or a related discipline, with several years post-PhD experience preferred. Also required is experience with a variety of commercial computational chemistry software and LINUX/UNIX systems.

Job Requisition #: 79659, St. Louis, MO

Please apply with Job Requisition #: 79659, at www.pfizer.jobs

To learn more about our people, our products, and our plans for the future, visit www.pfizer.jobs

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S.