Scientist - Bioinformatics

Codexis is a leading developer of proprietary biocatalysts that the
company believes have the potential to revolutionize chemistry-based
manufacturing processes across a variety of industries.
The company has used its technology platform to enable biocatalyst-based
commercial-scale drug manufacturing processes and delivered biocatalysts
and drug products to some of the worlds leading pharmaceutical companies.
Codexis has a funded collaboration in the biofuels market, and the
company is pursuing funded collaborations in several other bioindustrial
markets, including carbon management, water treatment and chemicals.

Job Description:
A scientist trained in computational modeling, structural biology, and/or
enzymology to design gene libraries for cellular and metabolic
engineering of biofuel producing organisms. The candidate should have
a strong understanding of directed evolution and pathway engineering; 
a proven record designing and analyzing metabolic pathways in silico; and
outstanding knowledge of microbial metabolism.

Requirements:

 -- Energetic, highly self-motivated, and able to work efficiently and
    productively in a start-up department

 -- Demonstrated ability to devise creative solutions to complex biological
    problems 

 -- Able to work independently and flexibly on a variety of projects-
    with good multitasking and organizational skills

 -- Ph.D. in Bioinformatics or Computational Biology.  Experience in the
    biotech industry is a plus, as is an understanding of LIMS systems 

 -- Able to discover novel targets for  metabolic engineering experiments
    based on computational modeling and expert knowledge

 -- Work with analytical chemists and LIMS specialists to keep the
   metabolic models updated with current experimental data

 -- Experienced in building and analyzing metabolic models, especially
    genome-scale models as well as microbial genome diversity mining

 -- Possessing strong statistical and analytical skills to interpret
    transcriptomics and metabolomics data

 -- Skilled in the techniques of Flux balance analysis, metabolic control
    analysis, and the development of novel metabolic pathways

The position comes with a competitive compensation and benefits package,
including stock options.  For more information about our plans for the
future, and to be considered for this career opportunity, please visit
www.codexis.com or click on
http://tbe.taleo.net/NA7/ats/careers/requisition.jsp?org=CODEXIS&cws=1&rid=146