From: jobs at ccl.net (do not send your application there!!!)<br />
To: jobs at ccl.net<br />
Date: Thu Jun 26 02:47:33 2008<br />
Subject: <STRONG>08.06.26 PhD scholarship in protein modelling, Perth, Australia</STRONG><br />

<pre>Biomolecular Modelling Group
Western Australian Biomedical Research Institute (WABRI)
School of Pharmacy
Curtin University of Technology, Perth, Australia

Ph.D. position in Protein Modelling.

The Biomolecular Modelling Group at WABRI has an opening for a highly
qualified Ph.D. research student with interests in applying molecular
dynamics simulation techniques to investigate the structure and function
of proteins. A SCHOLARSHIP (worth approximately AUD$21,000 per year and a
waiver of all university fees) is also offered. The successful applicant
will join a growing research group that will soon comprise three
postdoctoral research fellows, three PhD students and two honours students.
The group is headed by Dr. Ricardo L. Mancera. More details about the
group's research activities can be found at WABRI's website
(<a href="http://www.wabri.org.au/research/molec_modelling.html" target="_blank">http://www.wabri.org.au/research/molec_modelling.html</a>)

The research project that the student will work on involves the
characterisation of the oxygen tunnel in the enzyme cholesterol oxidase:
the tunnelling mechanism of oxygen into the active site, the conformational
changes in the protein associated with this process, the free energy
pathways for the diffusion of oxygen into the active site and the
relationship between the tunneling of oxygen and the redox mechanism of
action of the enzyme. This project will be carried out in collaboration
with Prof. Alice Vrielink at the University of Western Australia, who has
been determining very high resolution X-ray structures of cholesterol
oxidase for several years.

The position would be suitable for a student interested in using
established commercial and academic software, whilst providing an excellent
opportunity for those interested in computer programming and algorithm/
methods development. National and state high performance computing
facilities will be used to carry out some of the work.

Candidates must have completed by the time of enrolment a first-class or
upper-second class honours undergraduate degree and/or a masters degree in
chemistry, physics, materials science, biochemistry, chemical engineering
or related field. It is also a requirement for prospective applicants to
have demonstrable research experience in molecular dynamics simulations
and/or molecular modelling of proteins.

Curtin University of Technology (<a href="http://www.curtin.edu.au" target="_blank">http://www.curtin.edu.au</a>) is the largest 
university in Western Australia and is ranked amongst the top universities
in Australia. With its main campus located in the states capital Perth,
studying at Curtin offers the unique combination of excellent facilities
and highly qualified academic staff with a great lifestyle offered by
Western Australias superb weather, beaches and outdoors activities.
Curtin University is also the university with the largest population of
international students in Western Australia, offering an excellent
cultural, social and academic environment for students from all over the
world.

Only applicants that fulfill the above requirements need apply by
submitting a copy of their full CV to Dr. Ricardo L. Mancera
(R.Mancera:_:curtin.edu.au). The CV should contain full details of all
academic degrees obtained, previous research and work experience,
publications and conference presentations, and the names of 2-3 referees.</pre>
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