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CCL 10.05.14 Cheminformatics Research Associate | |||||||||
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From: jobs at ccl.net (do not send your application there!!!) To: jobs at ccl.net Date: Fri May 14 10:47:20 2010 Subject: 10.05.14 Cheminformatics Research Associate Job Summary: The Center for Molecular Innovation and Drug Discovery (CMIDD) at Northwestern University near Chicago, IL has an immediate opening for a Cheminformatics Specialist. This research position is responsible for the operation and maintenance of computational workflows supporting multi-investigator small molecule drug discovery, with an emphasis on the hit-to-lead stage. Primary workflows managed will include ones for compound and data management, search, and analysis; compound property and diversity analysis; virtual library enumeration and synthetic set design; bioisosteric elaboration; and pharmacophore and lead-hopping methods. Specific Responsibilities: - Oversees daily operation of cheminformatics tasks and workflows in support of a multiple-investigator industrialized academic hit-to-lead/hit-to-probe drug discovery center. - Operates, maintains, and develops PC- and server-based computational capabilities related to the hit-to-lead stage, as well as general lead and probe discovery efforts. - Integrates data input/output between workflow components and between workflows and users. - Participates in developing cheminformatics operations in response to changing Center needs, including development of the informatics associated with a first-stage compound storage plan. Minimum Qualifications: - A Ph.D. in Chemistry with relevant experience in small molecule cheminformatics, or a Ph.D. in Cheminformatics with experience in modern medicinal chemistry. - At least one year of postdoctoral or professional experience related to this position with evidence of productivity (publications or patents). - Experience with developing and maintaining cross-OS server- and PC-based advanced small molecule cheminformatic workflows and molecular modeling applications. - Experience with specific cheminformatic packages including Pipeline Pilot and OpenEye. - Track record of successful work in a modern research enterprise. - English fluency and excellent team, oral and written communication and reporting skills. Preferred Qualifications: - Two or more years of productive experience in a professional and technologically advanced work environment, with practical pharma experience most beneficial. - Experience with advanced Pipeline Pilot-based HTS followup, and virtual library and fragment/structure-based drug discovery computational workflows. - Unix-level operational ability, broad familiarity with practical small molecule computational tools (Accelrys, Tripos, CCG, MolNetworks, etc.), and ability to integrate selected tools via scripting. - Experience integrating small molecule and macromolecule representation and computation, including molecular modeling and virtual screening (e.g. Pymol, COOT, GRASP, GOLD, etc.). - Other advanced CAMD/CADD experience in a pharmaceutical context, and practical operational experience supporting multi-user computational needs. Submit application through Northwestern University's Job website http://www.northwestern.edu/hr/jobs/ Job ID: 15917, Job Title: Research Associate Must include salary requirement and contact information for 3 references.NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!! All @ signs were changed to :_: to fight spam. Before you send e-mail, you need to change :_: to @ For example: change joe:_:big123comp.com to joe@big123comp.com Please let your prospective employer know that you learned about the job from the Computational Chemistry List Job Listing at http://www.ccl.net/jobs. If you are not interested in this particular position yourself, pass it to someone who might be -- some day they may return the favor. |
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