2 Research Associates (Postdocs) and 4 PhD Studentships:
A Computational Framework for Metabolism

Unilever Centre for Molecular Informatics, Department of Chemistry
Cambridge University
http://www-ucc.ch.cam.ac.uk

The funds for the post-doctoral positions are available for two years
in the first instance. Funds for the PhD studentships are available
for three years.

The Unilever Centre for Molecular Sciences Informatics in Cambridge is
teaming up with Unilever plc to begin a major initiative in the study of
metabolism. Using computational and experimental data we wish to build
the necessary algorithms and software to predict the fate of food
ingredients, functionally active molecules and their metabolites.
It is expected that over the course of this project new tools for
data analysis will reveal underlying principles of metabolism, provide
predictive methods and identify opportunities to improve well-being
through healthy nutritional alternatives, better dietary compositions,
and products with specific health benefits.

The work will be performed in the Unilever Centre under the direction
of Professor Robert Glen and will include regular exchanges with project
and project leaders in Unilever. In the first phase of this project we
are seeking two post-doctoral scientists to start work immediately and
four PhD students to start from October 2010.

Post-Doctoral Positions
27,319 - 35,646 pa (UK pounds sterling)
PDM1: Predicting the sites and products of metabolism
PDM2: Modelling and understanding the function of metabolising enzymes

Applicants should have (or be about to receive) a PhD in chemistry or
related sciences, experience of writing computer software and ideally
demonstrate a strong interest in metabolism. Applications should include
a CV, publications list, contact details for three professional referees
and a completed form CHRIS/6 Parts I and III (downloadable from
http://www.admin.cam.ac.uk/offices/hr/forms/chris6/)

PhD Studentships
PhD1: Analysis and prediction of cytochrome p450 metabolism
PhD2: Estimating the physicochemical properties of metabolites
PhD3: Receptor activation and bioactivity of metabolites
PhD4: Chemical mechanisms of metabolising enzymes

Applicants should have obtained or expect to obtain, at least the
equivalent of a 2:1 UK honours degree in chemistry, biology or a related
scientific discipline and must have a good background knowledge in both
the life sciences and either data mining or computer science.
Applications should include a CV and contact details for two professional
referees. Owing to the limit of funding from the sponsor, these
studentships are open to EU citizens only.

All applications should be sent to
Mrs Susan Begg, Secretary to Professor Glen,
Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
United Kingdom
email: smb28*o*cam.ac.uk

Please quote reference: MA06665. Closing date: 30 June 2010.
The University is committed to Equality of Opportunity.