Scientific Computing Methods Developer- Computational Sciences CoE
Pfizer Inc.
Groton, CT, 06340

The CompSci CoE currently has an opening in our Groton research site
for a computational scientist to develop chemogenomics and systems
chemical biology algorithms and methods. Responsibilities will include
research and development of methods for modeling and visualizing
pharmacological profiles for the purpose of new target identification,
lead hopping, drug repurposing and safety profiling. 

As part of a multidisciplinary team you will develop innovative
computational solutions using linked data and semantic web technologies
that have direct positive impact on on-going pharmaceutical research
projects. Responsibilities include interacting with medicinal chemists,
biologists, ADME, and safety scientists to both identify on-going
project needs and promote computational solutions.

Qualifications:
This position requires a Ph.D. in a computational sciences based
discipline or a BS/MS with equivalent work experience. Advanced
knowledge of computational principles and knowledge of how to apply
these techniques to pharmaceutical research projects is required, along
with knowledge of pharmaceutical drug discovery and development
processes. Demonstrated experience in developing and applying
computational methods in one or more of the following areas:
chemogenomics/chemical biology, pathways/networks visualization,
selectivity analysis, machine learning methods. 

Technical qualifications include proficiency with (a) cheminformatics
methods and toolkits such as Pipeline Pilot, Accelyrs Accord SDK,
OpenEye OEChem, ChemAxon Marvin Beans and JChem (b) machine learning
and/or statistical modeling (c) demonstrated awareness of emerging
technologies in the field of chemogenomics and chemical biology network
analysis tools and methods and (d) track record of publications and
presentations in this area of research. In addition, experience working
with Linked Data and Semantic Web technologies is beneficial. The
ability to effectively work in a team environment is essential.

Throughout our 153 years, a legacy of caring for others has been at the
heart of everything we do at Pfizer. This commitment is no less
important when it comes to our employees. Pfizer wants to ensure that
employees have resources to help them develop and succeed both in their
careers and personal lives. One way we can achieve this is through our
comprehensive benefits program, which offers employees and their
eligible dependents the variety and flexibility to help address their
needs at different stages in life.

Pfizer is committed to equal opportunity in the terms and conditions of
employment for all employees and job applicants without regard to race,
color, religion, sex, sexual orientation, age, gender identity or
gender expression, national origin, disability or veteran status. All
applicants must have authorization to work for Pfizer in the U.S. In
certain circumstances it may be advantageous to Pfizer to support the
application(s) for temporary visa classification and/or sponsor
applications for permanent residence so that a foreign national
colleague can accept or remain in a work assignment in the U. S. 

For certain classes of temporary visas, the resulting work
authorization may be specific to Pfizer and the specific job and/or
work site. Pfizer may at its business discretion decide to or refrain
from obtaining, maintaining and/or extending the temporary visa status
and/or sponsoring a colleague for permanent residency and /or
employment eligibility, considering factors such as availability of
qualified U.S. workers and the colleague's long-term prospects for
securing lawful permanent residence, among other reasons. 

Employment applicants requiring immigration sponsorship must disclose,
when initial application for employment is made, whether or not they
are legally authorized to work for Pfizer in the U.S. and, if so,
whether that authorization permits them to work in the job they seek.
In no case should Pfizer's support of a colleague's temporary visa
application or sponsorship of a colleague for permanent residence be
construed to guarantee success of that application or amend or
otherwise invalidate the "at-will" employment relationship between the
colleague and Pfizer.

Salary commensurate with experience

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