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Date: Thu Oct 12 14:34:26 2017
Subject: 17.10.12 Senior Scientist, Computational Chemistry, Janssen R&D LLC, Spring House, PA, USA
Janssen Research & Development, a Johnson & Johnson Company is 
recruiting for a Senior Scientist, Computational Chemistry to be 
located Spring House, Pennsylvania.

The Lead Discovery organization within Janssen R&D is continuing to 
build key scientific expertise in screening, pharmacology and chemistry 
to partner closely with therapeutic area scientists to develop 
transformational new medicines in the areas of Oncology, Immunology, 
Neuroscience, Cardiovascular, and Infectious Diseases.  We are seeking 
outstanding drug discovery scientists to join our team to bring their 
expertise to exciting efforts in novel areas of drug discovery.  

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what 
matters most is helping people live full and healthy lives. We focus 
on treating, curing and preventing some of the most devastating and 
complex diseases of our time. And we pursue the most promising science, 
wherever it might be found. 

The Senior Scientist will apply computational methods, including 
structure-based drug design, homology modeling, QSAR, ligand/receptor 
docking, molecular dynamics, quantum methods and diversity/similarity 
analysis, in the design of individual molecules and libraries to 
advance various drug discovery projects.  You will participate in 
multi-disciplinary teams including chemists, biologists, and 
structural biologists providing key expertise in the use and 
interpretation of structural data related to drug targets and their 
ligands/inhibitors.  You will be responsible for: 
     Execution of sophisticated experiments using advanced 
        computational techniques on UNIX-based computer workstations.  
     Clear communication of the results of computational experiments 
        and interpretations of structure to team members facilitating 
        the discovery of new drugs is expected.
     Development of novel computational methods to address key drug 
        discovery questions.  

A minimum of a PhD in Computational Science or related discipline is 
A minimum of 5 years experience in the application of computational 
     chemistry tools to drug discovery is required. 
Familiarity with one or more standard computational chemistry packages 
     (Maestro/Schrodinger, MOE/Chemical Computing Group, OpenEye tools) 
     is expected. 
Ability to script work flows and implement new algorithms is preferred.  
Experience working with multi-disciplinary teams is required
Excellent communication skills are required. 
Experience with fragment-based ligand design is preferred.

Johnson & Johnson Family of Companies are equal opportunity employers,
and all qualified applicants will receive consideration for employment 
without regard to race, color, religion, sex, sexual orientation, 
gender identity, genetic information, national origin, protected 
veteran status, disability status, or any other characteristic 
protected by law.

Primary Location - United States-Pennsylvania-Spring House
Organization - Janssen Research & Development, LLC. (6084)
Job Function - Chemistry
Requisition ID - 9982170908
Apply directly on the JNJ careers website:
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Modified: Thu Oct 12 18:34:26 2017 GMT
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