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Date: Wed Feb 28 09:40:55 2018
Subject: 18.02.28 Principal Bioinformatician - MI/18/15 - Drug Discovery Unit
Principal Bioinformatician
	Starting salary from: 30,100-49,100 per annum (dependent upon experience) 
	Job Ref: MI/18/15 
	Duration: Fixed term until 31 March 2019 (in the first instance)

About the role:
As part of the expansion of the CRUK Manchester Institute Drug Discovery Unit
we are seeking an enthusiastic and proactive expert in Drug Discovery
Bioinformatics, to help drive our programmes from early target
identification through to candidate selection and clinical evaluation.  An
expert in the use of complex biological datasets to influence decision
making, you will play a significant role in the identification and
prioritisation of new drug discovery targets.  You will also have
significant influence in defining our biomarker strategy for patient
stratification and for validating in vivo markers of therapeutic response.

Alongside these project roles, you will influence and develop our group
capabilities and collaborations in bioinformatics and seek innovative ways
of interacting with our project teams to maximise the use of complex
biological datasets in the delivery of human drug candidates.  You will
also provide support and direction for the on-going support and future
enrichment of our Dotmatics informatics platform across all drug discovery

About you:
You should have a PhD in Biochemistry, Molecular Biology, Biology or
Bioinformatics (or related field) or a relevant postgraduate degree in
these disciplines plus substantial relevant experience in analysing
high-throughput genomics data sets.  In addition you will have significant
demonstrable experience analysing biological datasets including next
generation sequencing (NGS) and other genomic data.  

Why choose Cancer Research UK Manchester Institute?
The Cancer Research UK Manchester Institute (,
an Institute of The University of Manchester (, is a
world-leading centre for excellence in cancer research.  The Institute is
core funded by Cancer Research UK (, the largest
independent cancer research organisation in the world.  We are currently
situated at the internationally-renowned life sciences campus at Alderley
Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic
city surrounded by beautiful countryside.  
We are partnered with The Christie NHS Foundation Trust (adjacent to the
CRUK MI Paterson Building) in South Manchester (, one
of the largest cancer treatment centres in Europe.  These factors combine
to provide an exceptional environment in which to pursue basic,
translational and clinical research programmes.
For any informal enquiries about these posts, please contact Dr Allan
Jordan via email: allan.jordan-
The deadline for receipt of applications is: 29 March 2018.
How to apply?
To apply for this position please visit our website:
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