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Up Directory CCL 18.09.25 PhD or Postdoc: Regulation of Protein-Protein Interactions, MD and MC, CEITEC MU
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Date: Tue Sep 25 11:00:17 2018
Subject: 18.09.25 PhD or Postdoc: Regulation of Protein-Protein Interactions, MD and MC, CEITEC MU
Project: The project is focused on the regulation of protein interactions,
which have been associated with numerous diseases including cancer. The 
regulations involve posttranslational modifications, changes of salt 
and protein concentrations, or pH. Revealing and understanding these 
regulatory mechanisms is not only important general knowledge, but it 
could also be useful in the design of new treatments. The research will 
be strongly coupled to collaborations with excellent experimental teams 
and more closely discussed during the interview. The student will master 
the tools of multi-scale simulations using a wide range of techniques 
ranging from atomistic to coarse-grained simulations. Moreover, he/she 
will learn the advantages and disadvantages of various protein 
parameterizations, and advanced sampling techniques.

Eligibility: Outstanding candidates with experience in computer 
simulations and with an MSc degree in the fields of biophysics, soft 
matter physics, physical chemistry, computational chemistry, statistical 
mechanics, or related fields. Experience with molecular dynamics 
simulations (with GROMACS, CHARMM, NAMD, AMBER, LAMMPS, etc.) or other 
simulation techniques (Monte Carlo, DPD, etc.) at the atomistic or 
coarse-grained level would be an advantage.

Group info:
Applications must include a CV, list of publications, personal statement 
(description of research interests, past, and plans), and the names 
of 2 people willing to provide a letter of recommendation. Applications 
with all this material (preferably in a single pdf) should be sent 
to Robert Vacha (robert.vacha**
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Modified: Tue Sep 25 15:00:17 2018 GMT
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