|CCL 19.02.19 Senior Scientist/ Principal Scientist/ Director, Computational Chemistry; Cambridge, MA|
From: jobs at ccl.net (do not send your application there!!!)
To: jobs at ccl.net
Date: Wed Feb 20 17:50:58 2019
Subject: 19.02.19 Senior Scientist/ Principal Scientist/ Director, Computational Chemistry; Cambridge, MA
COMPANY DESCRIPTION Founded in 2016, Foghorn Therapeutics discovers and develops novel drugs to treat cancer and other serious medical disorders. The company seeks to discover novel therapeutics that target chromatin remodeling complexes. Foghorn uses a proprietary platform based on revolutionary advances in mechanistic understanding of disease. POSITION DESCRIPTION The successful candidate will be joining the computational chemistry team at Foghorn Therapeutics. He/she will be expected to drive and influence molecular design approaches by applying state of the art computational chemistry science. Of particular importance is the candidates ability to build strong working interactions with medicinal chemists and structural biologists. The successful candidate will be part of the chemistry team. Responsibilities include: - Work in close partnership with medicinal chemists as a united compound design team to improve potency, selectivity, and ADME properties while minimizing toxicological risk. - Help to further develop the computational chemistry infrastructure and software tools within Foghorn. - Develop deep understanding of project SAR, and in concert apply cutting edge computational chemistry methods to influence team strategy and compound design, and ultimately positively impact project direction - Maintain and develop working knowledge of contemporary computational chemistry methods and their use in ligand design and data analysis as applied to drug design projects. QUALIFICATIONS - Ph.D. in a relevant scientific discipline with at least 4+ years of Computational Chemistry experience within a biopharma company. - Sufficient experience and confidence to operate independently as the computational chemistry resource within the project team and represent computational chemistry in a variety of cross-functional contexts. - Strong familiarity with a wide range of current computational chemistry software tools. - Expert molecular designer with creativity & the ability to design ligands & libraries; utilizes tools to evaluate/prioritize ideas. - Highly collaborative, team oriented professional with a passion for drug design. - Experience with ligand and structure based computational chemistry activities. - A working knowledge of synthetic chemistry to enable independent compound design of synthetically tractable targets. - Model building and method development experience, informatics experience, and familiarity with high throughput screening, preferred but not required.
Please apply using the link below: https://foghorntherapeutics.applytojob.com/apply/J1kYNVPCLm/Senior-Scientist-PrinciNOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!
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