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Date: Tue Apr 16 22:53:02 2019
Subject: 19.04.16 Postdoctoral position in computational structure-based design and modeling, University of Maryland, IBBR, Rockville, MD

Postdoctoral position in computational structure-based design and modeling, University of Maryland, IBBR, Rockville, MD

Applications are invited for a Postdoctoral position in computational structure-based design and modeling of immune recognition and vaccine design at the University of Maryland Institute for Bioscience and Biotechnology Research (IBBR). Developing and employing cutting-edge algorithms to accurately model and engineer proteins of therapeutic and medical interest, we are located in a state-of-the-art facility in Rockville, MD with outstanding collaborators in structural biology, immunology, and vaccine design, and access to several high-performance computing clusters. Projects of interest include modeling and design of T cell receptor structure and antigen specificity, developing improved algorithms and energy functions to predict and engineer antibody binding, and designing novel vaccine immunogens. More information about the Pierce Lab and its research can be found at this site: .

IBBR ( ) is a premier research institute focused on the structural and quantitative biological characterization of complex protein structure/function relationships and bio-molecular engineering and testing of novel products or platforms targeting prevention or treatment of conditions of human disease and intervention. IBBR operates state-of-the-art facilities located in the heart of the biotechnology corridor in Rockville, Maryland. The Institute is a joint research enterprise between the University of Maryland and the National Institute of Standards and Technology and has an outstanding group of scientists and engineers with long-standing track records in basic and translational research.

Minimum Qualifications:

  • Ph.D. in bioinformatics, computational biology, biochemistry, or related field.
  • Experience in computational protein design, protein-protein docking and/or protein modeling, and use of software such as Rosetta and FoldX.
  • Excellent oral and written communication skills.


  • Familiarity with immune recognition, antibodies, or T cell receptors.
  • Experience developing or applying machine learning algorithms.

Applications: Applicants should send their CV, Cover letter and names/contact information of three references to:

Closing Date: Review of candidates will begin immediately and continue until the position is filled.

The University of Maryland, College Park, an equal opportunity/affirmative action employer, complies with all applicable federal and state laws and regulations regarding nondiscrimination and affirmative action; all qualified applicants will receive consideration for employment. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, religion, sex, national origin, physical or mental disability, protected veteran status, age, gender identity or expression, sexual orientation, creed, marital status, political affiliation, personal appearance, or on the basis of rights secured by the First Amendment, in all aspects of employment, educational programs and activities, and admissions.

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