|CCL 21.01.25 Computational Chemist|
From: jobs at ccl.net (do not send your application there!!!)
To: jobs at ccl.net
Date: Fri Feb 5 13:45:49 2021
Subject: 21.01.25 Computational Chemist
Computational Chemist https://apply.workable.com/deepcure/j/D662A40C47/ Description A stellar opportunity to join the core team of a growing startup: join DeepCure and have a lasting impact on redefining drug-discovery. As a Computational Chemist at DeepCure you will be at the heart of designing our transformative AI platform, work on the biggest challenges in the pharma industry, apply cutting-edge technologies, and help us shape the companys scientific vision ensuring we are constantly pushing the bar for what is possible. In this role you will work closely with our biology, medicinal chemistry, and machine learning team to push our programs and technology forward. ABOUT DEEPCURE: DeepCure, founded by a team of researchers from the MIT Media Lab, develops disruptive Artificial Intelligence to revolutionize pharmaceutical development. DeepCure redefines the way we discover new drugs by combining state-of-the-art Deep Learning algorithms, cloud-computing, our proprietary database of one Trillion molecules, and a unique approach to experimental data generation. Our mission is to deliver to patients safer and more effective therapeutics that are extremely unlikely to be discovered by any existing drug discovery pipeline. IN THIS ROLE YOU WILL: Be an important contributor in conceptualizing and designing DeepCures Computational Chemistry approach. Lead and support drug discovery campaigns as part of a biology, medicinal chemistry, and AI discovery team. Be an integral part of the decision making, development, and technical execution of DeepCures Computational Chemistry solutions. Collaborate closely with DeepCures AI team to maximize the impact of Computational Chemistry methods on our transformative AI platform. Apply Computational Chemistry and Cheminformatics methods to problems at all stages of the drug discovery process, from early target validation, hit-finding, lead optimization, and candidate delivery. Design and optimize novel drug candidates using state-of-the-art computational techniques such as protein modeling, molecular docking based on x-ray or homology models, ligand-based design, library design, diversity analysis, conformational analysis, and pharmacophore modeling. Conduct research into new Computational Chemistry tools and methods relevant to DeepCures mission. Requirements: Experience with small organic molecules A PERFECT CANDIDATE HAS: Deep passion for Artificial Intelligence and the future of drug development, as well as a desire to play a pivotal role in a nascent startup. Ph.D. in Computational Chemistry or a related discipline with 3 to 8 years industrial experience. A mission-driven attitude and natural problem-solving ability. An innovative and entrepreneurial mindset with sound scientific judgment. Ability to work at a fast pace and readily adopt new technologies and ways of thinking. Experience with scientific software such as Molecular Dynamics, FEP, Molecular Docking, Ligand-based design, cheminformatics, etc. Demonstrated understanding of all aspects of modern drug discovery including medicinal chemistry, DMPK principles, and multi-parameter optimization. The ability to prototype computational methods and programmatically automate basic tasks. Familiarity with software best-practices such as version control and testing is a plus. Applied experience and/or theoretical understanding of machine learning techniques is a plus. Demonstrated experience functioning within strong multi-disciplinary project teams. Excellent communication skills. Ability to communicate in an open, clear, timely and consistent manner. BENEFITS: For the right candidate, we'll offer a competitive salary plus equity. Your compensation is rounded out by a strong benefits package: Flexible work hours, with hybrid work-from-home and work-from-office options. Unlimited paid leave and sick time. Healthcare, vision, and dental insurance plans, with voluntary add-ons available for dependent care, life, and accident coverage. Commuter benefit for public transportation. Work in a cool and vibrant space at the heart of Boston. Snacks and drinks in the office. Most importantly, you'll have a huge impact, do important work, and work with a team of people you'll genuinely enjoy spending the day with. DeepCure is an equal opportunity employer, dedicated to creating a workplace that is free of harassment and discrimination. We base our employment decisions on business needs, job requirements, and qualifications that's all. We do not discriminate based on race, gender, religion, health, personal beliefs, age, family or parental status, or any other status. We don't tolerate any kind of discrimination or bias, and we are looking for teammates who feel the same way.
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