Subject: mutants with altered structures

From: Martín Lema <[email-masked]>
Date: Thu, 04 Apr 2002 11:04:04 -0300

Hello everybody:

We are looking for examples of protein mutants (with only one or two 
mutations) whose crystallographic structures have been determined 
experimentally, and exhibit a significantly altered structure (different 
backbone trace, gyration radius, local secondary structure) when compared 
to their wild type counterparts. Any hint is welcome.

Thanking in advance

Martin Lema
National University of Quilmes
Argentina