Subject: PoPMuSiC on the web

From: [email-masked]
Date: Wed, 25 Sep 2002 14:45:31 +0200

PoPMuSiC is an efficient tool for rational computer-aided
design of single-site mutations in proteins and peptides.
Two types of queries can be submitted. 
The first option allows to estimate the changes in folding free energy
for specific
point mutations given by the user. In the second option,
all possible point mutations in a given protein or protein region are
performed and the most stabilizing or destabilizing mutations, or the
neutral mutations with respect to thermodynamic stability, are selected.
For each sequence position or secondary structure the deviation
> from the most stable sequence is moreover
evaluated, which helps to identify the most suitable sites for
the introduction of mutations.

Availability: http://babylone.ulb.ac.be/popmusic

-- 
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Dr. BIOT Christophe
Ingenierie Biomoleculaire, CP 165/64
Universite Libre de Bruxelles
50, Av. F. Roosevelt
B-1050 Bruxelles
Belgique
Phone: 32-2-650 3001
Fax:   32-2-650 3606
E-mail:[email-masked]
http://babylone.ulb.ac.be/~christophe/
http://www.ulb.ac.be/rech/inventaire/unites/ULB163.html
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