Subject: Release of X-CScore v1.0: New scoring function available

From: "Renxiao Wang" <[email-masked]>
Date: Mon, 21 Oct 2002 11:35:57 -0400

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Dear All,

We would like to announce the release of X-CScore v1.0, a program for estimating protein-ligand binding affinites. Basically, X-CScore is a consensus scoring scheme that consists of three individual empirical scoring functions. It makes fast prediction based purely on protein-ligand complex structures and thus will see its major application to molecular docking approaches. The X-CScore algorithm is described in details on J. Comp.-Aided Mol. Des. 2002, 16:11-26.

We have set up a web site for releasing this program, which is at http://sw16.im.med.umich.edu/software/xtool/. All you need to do is to fill out a user license agreement and fax it to us, then you will receive an email describing how to download the whole X-CScore packet. The packet includes the source codes, user manual, and other supplementary material. The X-CScore program is written in ANSI C++ and has been tested on UNIX and LINUX platforms.

There is NO CHARGE for obtaining this program, applied to all the users from industry and academia. If you experience any problem in downloading or using this program, you may contact us directly.

Happy scoring,

Renxiao Wang, Ph.D.
Research Investigator
Department of Internal Medicine
University of Michigan Medical School
[email-masked]