6th AFMC International Medicinal Chemistry Congress

From owner-chemistry@ccl.net Wed Apr 4 13:45:01 2007 From: "Aleksandra N rudnitskaya aleksandra.rudnit001[A]umb.edu" To: CCL Subject: CCL:G: ts in gaussian Message-Id: <-33963-070404132626-9341-cB7nZv7ASW/mAbQAnUi+Fw,,server.ccl.net> X-Original-From: "Aleksandra N rudnitskaya" Date: Wed, 4 Apr 2007 13:26:22 -0400 Sent to CCL by: "Aleksandra N rudnitskaya" [aleksandra.rudnit001^^umb.edu] Hi, I work on the finding transitional states in reaction OH radical with linear hydrocarbons using everything in Gaussian 98. The reaction is Hydrocarbon +OH = H2O + Radical. Ive already tried everything I known: 1. TS opt=ts freq=noraman uhf/6-31+g It does not work because program doesnt recognize imaginary frequency while it is there I checked it with frequency job; 2. No Eigen Test and 3. Eigenvalue follow opt=(ts,noeigentest) freq=noraman uhf/6-31+g opt=(ts,ef) freq=noraman uhf/6-31+g Those guys dont work also. As the results Ive usually either product or reactant which is far apart from another molecule (OH radical or water molecule). 3. QST2/QST3 opt=(ts,qst2) freq=noraman uhf/6-31+g Its extremely hard to predict geometry of both reactants and products to get TS. Question: I took my linear hydrocarbon, optimized it and got geometry of first reactant. I did the same with OH radical and got the geometry of the second reactant. I took out one of the hydrogens from the linear hydrocarbon and optimized it. Now Ive got product geometry. I did the optimization on the second product water. Now, the hardest part, HOW TO COMBINE MY HYDROCARBON WITH OH, what position OH should occupy relative to hydrocarbon? Ones I fond solution for that problem, I may produce similar geometry (angles and dihedral angles) for radical and water molecule. There are millions of possible combinations. From my experience, its extremely hard to find distances, angles, and especially dihedral angles that are close enough to transitional states. When I construct wrong structure or even one that is not close enough to solution, file usually crashes and molecules go apart. How do you solve this problem? Is there any algorithm, any book? Thank you very much. Aleksandra From owner-chemistry@ccl.net Wed Apr 4 16:40:00 2007 From: "Cheri McFerrin cmcfer1]=[lsu.edu" To: CCL Subject: CCL:G: ts in gaussian Message-Id: <-33964-070404160210-17889-zOwLTmhGM9k2N/kC23QQCg-*-server.ccl.net> X-Original-From: "Cheri McFerrin" Content-Transfer-Encoding: 7bit Content-Type: multipart/alternative; boundary="_----------=_117571398827762" Date: Wed, 04 Apr 2007 14:13:08 -0500 MIME-Version: 1.0 Sent to CCL by: "Cheri McFerrin" [cmcfer1-,-lsu.edu] This is a multi-part message in MIME format. --_----------=_117571398827762 Content-Disposition: inline Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset="iso-8859-1" aleksandra create 2 jobs in 1. for example.. #uhf/basis freq followed by --Link1-- #uhf/basis opt=3D(readfc,saddle=3D1) freq ************************************************ the 2nd job will read the frequencies from the first and hopefully opt to a ts. cheri mcferrin ----- Original Message ----- From: "Aleksandra N rudnitskaya aleksandra.rudnit001[A]umb.edu" To: "McFerrin, Cheri Ann " Subject: CCL:G: ts in gaussian Date: Wed, 4 Apr 2007 13:26:22 -0400 Sent to CCL by: "Aleksandra N rudnitskaya" [aleksandra.rudnit001^^umb.edu] Hi, I work on the finding transitional states in reaction OH radical with linear hydrocarbons using everything in Gaussian 98. The reaction is Hydrocarbon +OH =3D H2O + Radical. Ive already tried everything I known: 1. TS opt=3Dts freq=3Dnoraman uhf/6-31+g It does not work because program doesnt recognize imaginary frequency while it is there I checked it with frequency job; 2. No Eigen Test and 3. Eigenvalue follow opt=3D(ts,noeigentest) freq=3Dnoraman uhf/6-31+g opt=3D(ts,ef) freq=3Dnoraman uhf/6-31+g Those guys dont work also. As the results Ive usually either product or reactant which is far apart from another molecule (OH radical or water molecule). 3. QST2/QST3 opt=3D(ts,qst2) freq=3Dnoraman uhf/6-31+g Its extremely hard to predict geometry of both reactants and products to get TS. Question: I took my linear hydrocarbon, optimized it and got geometry of first reactant. I did the same with OH radical and got the geometry of the second reactant. I took out one of the hydrogens from the linear hydrocarbon and optimized it. Now Ive got product geometry. I did the optimization on the second product water. Now, the hardest part, HOW TO COMBINE MY HYDROCARBON WITH OH, what position OH should occupy relative to hydrocarbon? Ones I fond solution for that problem, I may produce similar geometry (angles and dihedral angles) for radical and water molecule. There are millions of possible combinations. From my experience, its extremely hard to find distances, angles, and especially dihedral angles that are close enough to transitional states. When I construct wrong structure or even one that is not close enough to solution, file usually crashes and molecules go apart. How do you solve this problem? Is there any algorithm, any book? Thank you very much. Aleksandra -=3D This is automatically added to each message by the mailing script =3D-http://www.ccl.net/cgi-bin/ccl/send_ccl_messagehttp://www.ccl.net/chemistry/sub_unsub.shtmlhttp://www.ccl.net/spammers.txt--_----------=_117571398827762 Content-Disposition: inline Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="iso-8859-1"

aleksandra

create 2 jobs in 1. for example..

#uhf/basis freq

followed by

--Link1--

#uhf/basis opt=3D(readfc,saddle=3D1) freq

************************************************

the 2nd job will read the frequencies from the first and hopefully opt t= o a ts.

cheri mcferrin

----- Original Message -----
From: "Aleksandra N rudnitsk= aya aleksandra.rudnit001[A]umb.edu"
To: "McFer= rin, Cheri Ann "
Subject: CCL:G: ts in gaussia= n
Date: Wed, 4 Apr 2007 13:26:22 -0400

Sent to CCL by: "A= leksandra N rudnitskaya" [aleksandra.rudnit001^^umb.edu]
Hi,

I wo= rk on the finding transitional states in reaction OH radical
with linea= r hydrocarbons using everything in Gaussian 98. The
reaction is
Hydr= ocarbon +OH =3D H2O + Radical.

Ive already tried everything I known:=
1. TS
opt=3Dts freq=3Dnoraman uhf/6-31+g
It does not work because= program doesnt recognize imaginary
frequency while it is there I check= ed it with frequency job;
2. No Eigen Test and 3. Eigenvalue follow
o= pt=3D(ts,noeigentest) freq=3Dnoraman uhf/6-31+g
opt=3D(ts,ef) freq=3Dnor= aman uhf/6-31+g
Those guys dont work also. As the results Ive usually ei= ther
product or reactant which is far apart from another molecule (OH <= BR>radical or water molecule).
3. QST2/QST3
opt=3D(ts,qst2) freq=3Dno= raman uhf/6-31+g
Its extremely hard to predict geometry of both reactant= s and
products to get TS.

Question:

I took my linear hydr= ocarbon, optimized it and got geometry of first reactant.
I did the same= with OH radical and got the geometry of the second reactant.
I took out= one of the hydrogens from the linear hydrocarbon and
optimized it. Now= Ive got product geometry. I did the optimization
on the second product= water. Now, the hardest part, HOW TO COMBINE
MY HYDROCARBON WITH OH, w= hat position OH should occupy relative to
hydrocarbon? Ones I fond solu= tion for that problem, I may produce
similar geometry (angles and dihed= ral angles) for radical and water
molecule. There are millions of possi= ble combinations. From my
experience, its extremely hard to find distan= ces, angles, and
especially dihedral angles that are close enough to tr= ansitional
states. When I construct wrong structure or even one that is= not
close enough to solution, file usually crashes and molecules go apart.

How do you solve this problem? Is there any algorithm, any = book?

Thank you very much.

Aleksandra

-=3D Thi= s is automatically added to each message by the mailing script =3D-
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--_----------=_117571398827762-- From owner-chemistry@ccl.net Wed Apr 4 17:14:00 2007 From: "Steve Williams willsd_+_appstate.edu" To: CCL Subject: CCL:G: ts in gaussian Message-Id: <-33965-070404164742-26256-r/QrF3YEqxwUle6vJ3GFsg#server.ccl.net> X-Original-From: Steve Williams Content-Transfer-Encoding: 7bit Content-Type: text/plain; charset=ISO-8859-1; format=flowed Date: Wed, 04 Apr 2007 15:40:12 -0400 MIME-Version: 1.0 Sent to CCL by: Steve Williams [willsd#appstate.edu] I'd recommend adding two more tricks to your list: 1) Add calcfc to opt=, or for nasty cases, calcall. Try something like opt=(ts, noeigentest, calcfc). These both use a high quality hessian to start the ts optimization; the first computes the "exact" hessian only at the beginning of the optimization; the second (much slower!) computes the "exact" hessian at each step. 2) For a method intermediate between these, I have sometimes had success with opt=(ts, noeigentest, calcfc, maxcycle=10); after the 10 steps do another freq calculation to make sure the optimization is still following the correct reaction coordinate; if so repeat the above for 10 more steps. This is a sort of "calc-sometimes" method. 3) It may very well be the case that uhf/6-31+g is too low a level of theory to find the ts... If you can afford it, I'd recommend mp2, or a hybrid dft method, like b3lyp. The hybrid dft will be slower than uhf, but a quite a bit faster then mp2. I have used mp2 with OH radical reactions fo rjust this reason. Good luck! Steve Williams Aleksandra N rudnitskaya aleksandra.rudnit001[A]umb.edu wrote: > Sent to CCL by: "Aleksandra N rudnitskaya" [aleksandra.rudnit001^^umb.edu] > Hi, > > I work on the finding transitional states in reaction OH radical with linear hydrocarbons using everything in Gaussian 98. The reaction is > Hydrocarbon +OH = H2O + Radical. > > Ive already tried everything I known: > 1. TS > opt=ts freq=noraman uhf/6-31+g > It does not work because program doesnt recognize imaginary frequency while it is there I checked it with frequency job; > 2. No Eigen Test and 3. Eigenvalue follow > opt=(ts,noeigentest) freq=noraman uhf/6-31+g > opt=(ts,ef) freq=noraman uhf/6-31+g > Those guys dont work also. As the results Ive usually either product or reactant which is far apart from another molecule (OH radical or water molecule). > 3. QST2/QST3 > opt=(ts,qst2) freq=noraman uhf/6-31+g > Its extremely hard to predict geometry of both reactants and products to get TS. > > Question: > > I took my linear hydrocarbon, optimized it and got geometry of first reactant. > I did the same with OH radical and got the geometry of the second reactant. > I took out one of the hydrogens from the linear hydrocarbon and optimized it. Now Ive got product geometry. I did the optimization on the second product water. Now, the hardest part, HOW TO COMBINE MY HYDROCARBON WITH OH, what position OH should occupy relative to hydrocarbon? Ones I fond solution for that problem, I may produce similar geometry (angles and dihedral angles) for radical and water molecule. There are millions of possible combinations. From my experience, its extremely hard to find distances, angles, and especially dihedral angles that are close enough to transitional states. When I construct wrong structure or even one that is not close enough to solution, file usually crashes and molecules go apart. > > How do you solve this problem? Is there any algorithm, any book? > > Thank you very much. > > Aleksandra> > > > From owner-chemistry@ccl.net Wed Apr 4 18:19:01 2007 From: "Dan Fara DFara-.-salud.unm.edu" To: CCL Subject: CCL: melting point Message-Id: <-33966-070404135557-16443-DFeECIbjLmOglzDr6tBeVQ##server.ccl.net> X-Original-From: "Dan Fara" Content-Type: multipart/alternative; boundary="=__Part4A6D12AB.0__=" Date: Wed, 04 Apr 2007 11:13:31 -0600 Mime-Version: 1.0 Sent to CCL by: "Dan Fara" [DFara(!)salud.unm.edu] This is a MIME message. If you are reading this text, you may want to consider changing to a mail reader or gateway that understands how to properly handle MIME multipart messages. --=__Part4A6D12AB.0__= Content-Type: text/plain; charset=US-ASCII Content-Transfer-Encoding: quoted-printable I got it. Thanks. =20 Dan Fara >>> "Soren Eustis soren_+_jhu.edu" 4/3/2007 9:20 = PM >>> Sent to CCL by: "Soren Eustis" [soren##jhu.edu] The EPA EPIWin package can do this. Go to epa.gov and search for epiwin. You ought to be able to find it. Soren Eustis -----Original Message----- > From: owner-chemistry[#]ccl.net [mailto:owner-chemistry[#]ccl.net]=20 Sent: Tuesday, April 03, 2007 11:47 AM To: Eustis, Soren=20 Subject: CCL: melting point Sent to CCL by: "Dan C Fara" [dfara!A!salud.unm.edu] Dear All: Is there any free software that can be used for estimating the melting = point values of organic compounds? Thanks. Dan Fara Univ. of New Mexico, Division of Biocomputinghttp://www.ccl.net/cgi-bin/ccl= /send_ccl_messagehttp://www.ccl.net/chemistry/sub_unsub.shtmlhttp://www.ccl= .net/spammers.txt -=3D This is automatically added to each message by the mailing script = =3D-http://www.ccl.net/cgi-bin/ccl/send_ccl_message=20=20 Subscribe/Unsubscribe:=20=20( http://www.ccl.net= / ) Job: http://www.ccl.net/jobs=20=20http://www.ccl.net/spammers.txt=20=20--=__Part4A6D12AB.0__= Content-Type: text/html; charset=US-ASCII Content-Transfer-Encoding: quoted-printable Content-Description: HTML

I got it. Thanks.

Dan Fara

>>> "Soren Eustis soren_+_jhu.edu" <owner-= chemistry*_*ccl.net> 4/3/2007 9:20 PM >>>

Sent to CCL by: = "Soren Eustis" [soren##jhu.edu]
The EPA EPIWin package can do this. = ; Go to epa.gov and search for epiwin.
You ought to be able to find = it.

Soren Eustis

-----Original Message-----
> = > From: owner-chemistry[#]ccl.net [mailto:owner-chemistry[#]ccl.net] =
Sent: Tuesday, April 03, 2007 11:47 AM
To: Eustis, Soren
Subject= : CCL: melting point

Sent to CCL by: "Dan C Fara" [dfara!A!salud= .unm.edu]

Dear All:

Is there any free software that can be = used for estimating the melting point
values of organic compounds?
Thanks.

Dan Fara

Univ. of New Mexico, Division of = Biocomputinghttp://www.ccl.net/cgi-bin/ccl/send_ccl_messagehttp://www.ccl.n= et/chemistry/sub_unsub.shtmlhttp://www.ccl.net/spammers.txt

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--=__Part4A6D12AB.0__=-- From owner-chemistry@ccl.net Wed Apr 4 20:28:00 2007 From: "Dave Winkler dave.winkler:-:csiro.au" To: CCL Subject: CCL: 6th AFMC International Medicinal Chemistry Congress Message-Id: <-33967-070404201053-17865-yGBoDJIRPx4qWZyVcjwL2g+*+server.ccl.net> X-Original-From: Dave Winkler Content-Type: multipart/Related; boundary="============_-1036392770==_mr============" ; type="text/html" Date: Thu, 5 Apr 2007 09:35:24 +1000 Mime-Version: 1.0 Sent to CCL by: Dave Winkler [dave.winkler:_:csiro.au] --============_-1036392770==_mr============ Content-Type: multipart/alternative; boundary="============_-1036392770==_ma============" --============_-1036392770==_ma============ Content-Type: text/plain; charset="iso-8859-1" ; format="flowed" Content-Transfer-Encoding: quoted-printable Dear colleagues, The Asian Federation for Medicinal Chemistry (the=20 sister organization of the EFMC) is holding its=20 two-yearly major congress on medicinal chemistry=20 in the beautiful and exotic city of Istanbul next=20 July. The abstract submission and registration=20 date close soon and we invite medicinal and=20 computational chemists to attend this significant=20 conference. Symposium Session Topics Scientific program of the symposium consists of=20 Plenary Lectures, Invited Lectures, and Oral and=20 Poster presentations from contributed abstracts.=20 Abstract submission on the below topics is=20 anticipated. * Chemistry and biology for pharmaceuticals New synthetic methods Process chemistry Biomimetics Chemical genomics * New Drug Development on the basis of New Drug Targets Endogenous substances Receptors, enzymes, channels Glycoproteins Genomic pharmacology * ADME/Tox. Drug metabolism and toxicology Drug delivery Medicinal bioengineering Biomaterials * New methods for drug discovery Analytical & physico-pharmaceutical chemistry High-throughput medicinal & combinatorial advances Lead identification & optimization Glycotechnology * Predictive in silico methods Bioinformatics Structural biology for drug development Complex systems approaches Cheminformatics and QSAR Computational chemistry * Protein-Protein Interactions (EFMC Session) * Reversal of multi-drug resistance New Antibiotics New Antifungal Agents New Antiviral Agents * Natural Products Biological/Physiological activities * Recent approaches in anticancer therapy * Biomarkers in HTS through preclinical and clinical development * Intellectual Property (IP) and Regulatory affairs Patenting Clinical trials issues Registration issues Spinoffs and new businesses * * Biosynthetic Medicinal Chemistry (ACS, MC Session) Modulation of bioactive=20 natural products by synthetic biology and=20 chemistry Please excuse duplicate postings. >> >> >> >> >>Dear Colleague, >> >>On behalf of Organizing Committee, we are kindly informing you that the >>The=20 >>Second Circular & Call for Papers for >>The 6th AFMC International Medicinal Chemistry Symposium (AIMECS 07) >>that will be held in Istanbul, Turkey on 08-11 July, 2007, >>is ready to reach at the Symposium Internet Web=20 >>page=20 >>http://www.aimecs07.org=20 >>. >> >>If you visit the last updated AIMECS 07=20 >>Internet Web page=20 >>http://www.aimecs07.org=20 >>you can find the detailed information's about: >> <> >>v Symposium Topics, >>v Preliminary Programm= e, >>v Confirmed Lecturers, >>v =20 >>Online=20 >>Early Registration, >>v =20 >>Online=20 >>Abstract Submission, >>v =20 >>Online=20 >>Hotel Accommodation, >>v =20 >>Exhibition=20 >>Registration, >>v =20 >>Daily/Post-Congress=20 >>Tour Options. >> >>The Organizing Committee of AIMECS 07 strongly=20 >>suggests you to be one of the privileged=20 >>participants of this Asian Federation for=20 >>Medicinal Chemistry (AFMC) Symposium and kindly=20 >>invites you to register and send an abstract to=20 >>the 6th AFMC International Medicinal Chemistry=20 >>Symposium, 08-11 July 2007, Istanbul, Turkey". >> >>The Organizing Committee cordially informs you; >>=FC Deadline for Abstracts Submission is April 15, 2007 >>=FC Deadline for Early Registration is April 30, 2007 >>=FC Deadline for Hotel Reservation is May 15, 2007 >>It is our intention to make this biennial Asian=20 >>Federation for Medicinal Chemistry (AFMC)=20 >>International Med. Chem. Symposium a memorable=20 >>event, both scientifically and socially for the=20 >>attendees. >> >>We look forward to welcoming you in Istanbul. >> >>Kind regards, >> >> Prof. Ismail Yalcin=20 >> Prof. Esin Aki (Sener) >>(AFMC President & Symposium Chairman)=20 >>(Organization Committee Chair of AIMECS 07) >> > > > >-- > >Cheers, >Dave > >Dr. David A. Winkler FRACI CChem CPChem Email: dave.winkler .. csiro.au >CSIRO Centre for Complexity in Drug Design Voice: 61-3-9545-2477 >Senior Principal Research Scientist Fax: 61-3-9545-2561 >CSIRO Molecular and Health Technologies or 61-3-9545-2446 >Private Bag 10,Clayton South MDC 3169 http://www.csiro.au >Australia http://www.molsci.csiro.au > >http://www.csiro.au/csiro/content/standard/ps1gn,,.html=20 >or http://www.wark.csiro.au/winkler/Welcome.html > >Join us at the 12th Asian Chemical Congress*=20 >(12ACC) August 23 - 25, 2007, Kuala Lumpur=20 >(Joint with the RACI)=20 >http://www.ikm.org.my/12ACC_brochure.htm and the=20 >6th International Medicinal Chemistry Symposium=20 >(AIMECS07) July 08-11, 2007, Istanbul Turkey=20 >http://www.aimecs07.org/index.php -- Cheers, Dave Prof. David A. Winkler FRACI CChem CPChem Email: dave.winkler .. csiro.au CSIRO Centre for Complexity in Drug Design Voice: 61-3-9545-2477 Senior Principal Research Scientist Fax: 61-3-9545-2561 CSIRO Molecular and Health Technologies or 61-3-9545-2446 Private Bag 10,Clayton South MDC 3169 http://www.csiro.au Australia http://www.molsci.csiro.au Join us at the 12th Asian Chemical Congress*=20 (12ACC) August 23 - 25, 2007, Kuala Lumpur (Joint=20 with the RACI)=20 http://www.ikm.org.my/12ACC_brochure.htm and the=20 6th International Medicinal Chemistry Symposium=20 (AIMECS07) July 08-11, 2007, Istanbul Turkey=20 http://www.aimecs07.org/index.php --============_-1036392770==_ma============ Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable 6th AFMC International Medicinal Chemistry Congress

Dear colleagues,

The Asian Federation for Medicinal Chemistry (the sister organization of the EFMC) is holding its two-yearly major congress on medicinal chemistry in the beautiful and exotic city of Istanbul next July. The abstract submission and registration date close soon and we invite medicinal and computational chemists to attend this significant conference.

Symposium Session Topics
Scientific program of the symposium consists of Plenary Lectures, Invited Lectures, and Oral and Poster presentations from contributed abstracts. Abstract submission on the below topics is anticipated.
* Chemistry and biology for pharmaceuticals

New synthetic methods

Process chemistry

Biomimetics

Chemical genomics

* New Drug Development on the basis of New Drug Targets

Endogenous substances

Receptors, enzymes, channels

Glycoproteins

Genomic pharmacology

* ADME/Tox.

Drug metabolism and toxicology

Drug delivery

Medicinal bioengineering

Biomaterials

* New methods for drug discovery

Analytical & physico-pharmaceutical chemistry

High-throughput medicinal & combinatorial advances

Lead identification & optimization

Glycotechnology

* Predictive in silico methods

Bioinformatics

Structural biology for drug development

Complex systems approaches

Cheminformatics and QSAR

Computational chemistry

* Protein-Protein Interactions (EFMC Session)

* Reversal of multi-drug resistance

New Antibiotics

New Antifungal Agents

        New Antiviral Agents

    *       Natural Products Biological/Physiological activities

    *       Recent approaches in anticancer therapy

*       Biomarkers in HTS through preclinical and clinical development

*       Intellectual Property (IP) and Regulatory affairs

Patenting

Clinical trials issues

Registration issues

        Spinoffs and new businesses
     *
        *       Biosynthetic Medicinal Chemistry (ACS, MC Session)

Modulation of bioactive natural products by synthetic biology and chemistry

Please excuse duplicate postings.

Dear Colleague,

On behalf of Organizing Committee, we are kindly informing you that the

The Second Circular &am= p; Call for Papers for

The 6th AFMC International Medicinal Chemistry Symposium (AIMECS 07)

that will be held in Istanbul, Turkey on 08-11 July, 2007,

is ready to reach at the Symposium Internet Web page http://www.aimecs07.org .

If you visit the last updated AIMECS 07 Internet Web page http://www.aimecs07.org you can find the detailed information's about:

v        Symposium Topics,

v        Preliminary Programme,

v        Confirmed Lecturers,

v        Online Early Registration,

v        Online Abstract Submission,

v        Online Hotel Accommodation,

v        Exhibition Registration,

v        Daily/Post-Congress Tour Options.

The Organizing Committee of AIMECS 07 strongly suggests you to be one of the privileged participants of this Asian =46ederation for Medicinal Chemistry (AFMC) Symposium and kindly invites you to register and send an abstract to the 6th AFMC International Medicinal Chemistry Symposium, 08-11 July 2007, Istanbul, Turkey".

The Organizing Committee cordially informs you;

=FC     Deadline for Abstracts Submission is April 15, 2007

=FC     Deadline for Early Registration is April 30, 2007

=FC     Deadline for Hotel Reservation is May 15, 2007

It is our intention to make this biennial Asian =46ederation for Medicinal Chemistry (AFMC) International Med. Chem. Symposium a memorable event, both scientifically and socially for the attendees.

We look forward to welcoming you in Istanbul.

Kind regards,

      Prof. Ismail Yalcin                                                   Prof. Esin Aki (Sener)

(AFMC President & Symposium Chairman)                    (Organization Committee Chair of AIMECS 07)

--

Cheers,
Dave

Dr. David A. Winkler FRACI CChem CPChem      Email: dave.winkler .. csiro.au
CSIRO Centre for Complexity in Drug Design        Voice: 61-3-9545-2477
Senior Principal Research Scientist                Fax: 61-3-9545-2561
CSIRO Molecular and Health Technologies     or 61-3-9545-2446
Private Bag 10,Clayton South MDC 3169 http://www.csiro.au
Australia                                    http://www.molsci.csiro.au

http://www.csiro.au/csiro/content/standard/ps1gn,,.html or http://www.wark.csiro.au/winkler/Welcome.html

Join us at the 12th Asian Chemical Congress* (12ACC) August 23 - 25, 2007, Kuala Lumpur (Joint with the RACI) http://www.ikm.org.my/12ACC_brochure.htm and the 6th International Medicinal Chemistry Symposium (AIMECS07) July 08-11, 2007, Istanbul Turkey http://www.aimecs07.org/index.php

--

Cheers,
Dave

Prof. David A. Winkler FRACI CChem CPChem    Email: dave.winkler .. csiro.au
CSIRO Centre for Complexity in Drug Design        Voice: 61-3-9545-2477
Senior Principal Research Scientist                Fax: 61-3-9545-2561
CSIRO Molecular and Health Technologies     or 61-3-9545-2446
Private Bag 10,Clayton South MDC 3169 http://www.csiro.au
Australia                                    http://www.molsci.csiro.au

Join us at the 12th Asian Chemical Congress* (12ACC) August 23 - 25, 2007, Kuala Lumpur (Joint with the RACI) http://www.ikm.org.my/12ACC_brochure.htm and the 6th International Medicinal Chemistry Symposium (AIMECS07) July 08-11, 2007, Istanbul Turkey http://www.aimecs07.org/index.php
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