From owner-chemistry@ccl.net Wed May 28 03:40:00 2008
From: "Ulrich Scharfenort scharfenort(a)ltt.rwth-aachen.de" <owner-chemistry\a/server.ccl.net>
To: CCL
Subject: CCL:G: G Polarizibiliy at imaginary Frequencies
Message-Id: <-37049-080527024213-23664-xr8BkJQfHNXh0DJBtskzIA\a/server.ccl.net>
X-Original-From: Ulrich Scharfenort <scharfenort * ltt.rwth-aachen.de>
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Date: Tue, 27 May 2008 08:41:50 +0200
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Sent to CCL by: Ulrich Scharfenort [scharfenort|*|ltt.rwth-aachen.de]

Hello,

is it possible to calculate polarizibilities with Gaussian03 at 
imaginary frequencies?
If possible: How does an input file for this task looking?

Thanks

Ulrich Scharfenort


From owner-chemistry@ccl.net Wed May 28 04:39:01 2008
From: "Sina T reli sinatureli{}gmail.com" <owner-chemistry.:.server.ccl.net>
To: CCL
Subject: CCL: Floating Point Math Errors
Message-Id: <-37050-080528043432-11790-/kQqxWRPtXBwAsOfnTCXPg.:.server.ccl.net>
X-Original-From: "Sina  T  reli" <sinatureli:-:gmail.com>
Date: Wed, 28 May 2008 04:34:27 -0400


Sent to CCL by: "Sina  T  reli" [sinatureli%a%gmail.com]
Hello,

I am working on a project related to proteins and my precision for coordinates is there digits after the dot. When I do operations like rotation around a dihedral, the dihedrals which shouldn't change change at about 0.01 angles and so. I am afraid though that is not much it might accumulate over time. So do you have any suggestions for reducing floating integer errors? Would't be feasible if I turned lets say the coordinate 21.567 to 21567 and do my operations? Or maybe even 215670?

Thanks


From owner-chemistry@ccl.net Wed May 28 09:16:01 2008
From: "gajuguard-ccl{:}yahoo.co.in" <owner-chemistry.@.server.ccl.net>
To: CCL
Subject: CCL: Which Drug Design s/w to be Bought for Academic Research
Message-Id: <-37051-080527095202-5690-bP80qyjeyaNQQXdqqsnzsg.@.server.ccl.net>
X-Original-From: gajuguard-ccl::yahoo.co.in
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Date: Tue, 27 May 2008 18:21:45 +0530 (IST)
MIME-Version: 1.0


Sent to CCL by: gajuguard-ccl^^^yahoo.co.in

--0-901870661-1211892705=:80958
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Respected Sir / Madam,
&nbsp;
Our's is the Pharmacy Dept in the SGSITS, an Autonomous Institute in MP, IN=
DIA.
We are in process to buy a drug design software for the purpose of doing ba=
sic research in drug design (non-profit purpose) for
- QSAR
- Docking=20
-&nbsp;Pharmacophore modeling
- prediction of ADME parameters=20
- &amp; other accessories
&nbsp;
So, we are in search of a drug design software to be bought in thedept't&nb=
sp;which is economic, with out&nbsp;time limitation, with neccessary accura=
ry &amp; predictability in results for academic research.
&nbsp;
Kindly have some suggestions.
&nbsp;
Thanking you.
&nbsp;
Sincerely,
Gajanan Wanare,
Dept't of Pharmacy,
Shri G S Institute of Technology &amp; Science (SGSITS),
Indore- (MP) INDIA.
www.sgsits.ac.in
gajuguard-ccl---yahoo.co.in=0A=0A=0A      Best Jokes, Best Friends, Best Food=
 and more. Go to http://in.promos.yahoo.com/groups/bestofyahoo/
--0-901870661-1211892705=:80958
Content-Type: text/html; charset=utf-8
Content-Transfer-Encoding: quoted-printable

<table cellspacing=3D'0' cellpadding=3D'0' border=3D'0' background=3D'none'=
 style=3D'font-family:arial;font-size:10pt;color:#000000;background-color:#=
ffffff;width:100%;'><tr><td valign=3D'top' style=3D'font: inherit;'><DIV>Re=
spected Sir / Madam,</DIV>
<DIV>&nbsp;</DIV>
<DIV>Our's is the Pharmacy Dept in the SGSITS, an Autonomous Institute in M=
P, INDIA.</DIV>
<DIV>We are in process to buy a drug design software for the purpose of doi=
ng basic research in drug design (non-profit purpose) for</DIV>
<DIV>- QSAR</DIV>
<DIV>- Docking </DIV>
<DIV>-&nbsp;Pharmacophore modeling</DIV>
<DIV>- prediction of ADME parameters </DIV>
<DIV>- &amp; other accessories</DIV>
<DIV>&nbsp;</DIV>
<DIV>So, we are in search of a drug design software to be bought in thedept=
't&nbsp;which is economic, with out&nbsp;time limitation, with neccessary a=
ccurary &amp; predictability in results for academic research.</DIV>
<DIV>&nbsp;</DIV>
<DIV>Kindly have some suggestions.</DIV>
<DIV>&nbsp;</DIV>
<DIV>Thanking you.</DIV>
<DIV>&nbsp;</DIV>
<DIV>Sincerely,</DIV>
<DIV>Gajanan Wanare,</DIV>
<DIV>Dept't of Pharmacy,</DIV>
<DIV>Shri G S Institute of Technology &amp; Science (SGSITS),</DIV>
<DIV>Indore- (MP) INDIA.</DIV>
<DIV><A href=3D"http://www.sgsits.ac.in/">www.sgsits.ac.in</A></DIV>
<DIV><A href=3D"mailto:gajuguard-ccl---yahoo.co.in">gajuguard-ccl---yahoo.co.in=
</A></DIV></td></tr></table><br>=0A=0A=0A      <!--11--><hr size=3D1></hr> =
Best Jokes, Best Friends, Best Food. Get all this and more on <a href=3D"ht=
tp://in.rd.yahoo.com/tagline_groups_11/*http://in.promos.yahoo.com/groups/b=
estofyahoo/"> Best of Yahoo! Groups.</a>
--0-901870661-1211892705=:80958--


From owner-chemistry@ccl.net Wed May 28 09:51:01 2008
From: "Peter Bladon p.bladon~~strath.ac.uk" <owner-chemistry|a|server.ccl.net>
To: CCL
Subject: CCL: Unambigous comparison of 3D structures
Message-Id: <-37052-080527181926-10041-FWMCCfQjw99NiXxqmOuQ6g|a|server.ccl.net>
X-Original-From: "Peter Bladon" <p.bladon(~)strath.ac.uk>
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Date: Tue, 27 May 2008 22:39:35 +0100
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Sent to CCL by: "Peter Bladon" [p.bladon]^[strath.ac.uk]

Dear David
=20
There are facilities in the Interprobe software for doing some of the =
tasks;=20
they might need to be adapted if your aim is to do large numbers of =
comparisons.
The program called PROTEINS will abstract individual structures =
(including the
ligands) from the PDB, in a form that will allow you to separate the =
ligand from the
protein using the program INTERCHEM.
The programs THREEDOM allows different poses of a single ligand (or =
different ligands)
to be superimposed.  The superimposition does not require any atom to =
atom correlations,=20
nor on the corresponding atoms in different poses being ordered in the =
same way. It
relies entirely on the overall shapes of the poses.  It will fail in =
extreme cases where the
poses are very different, or where the shape of the ligand has some =
apparent symmetry.=20
In general the superimposition will give you a  measure of the =
similarity of the poses.=20
=20
Because the PDB structures do not usually have hydrogens, you will need =
a method of=20
adding hydrogens. The program INTERCHEM will allow you to remove =
hydrogens (this
would suffice in preliminary trials).
=20
If you need help or further explananations please contact me.
=20
Dr. Peter Bladon
Interprobe Chemical Services
Telephone: +44-(0)141-578-1109
Facsimile: +44-(0)141-776-7712
e-mail:    cbas25*o*strath.ac.uk
URL:      http://www.interprobe.co.uk/interprobe.html  =20
=20

________________________________

> From: David D phrm75{:}yahoo.com [mailto:owner-chemistry*o*ccl.net]
Sent: Thu 22-May-08 21:34
To: Bladon, Peter 
Subject: CCL: Unambigous comparison of 3D structures


Hello,
I need to perform analysis changes in 3D structures of small molecules =
in different PDB files. One way of doing this is to superimpose the =
molecules. The problem is that superposition algorithms need user input =
of paired atoms. Otherwise, unattended superposition results may depend =
on the initial orientation of the two molecules. Superposition is =
especially problematic in the case of molecules with multiple symmetry =
axes. Another possibility is to create connectivity matrix file =
(Z-matrix) that will contain molecules internal coordinates. Here, =
unattended processes rely heavily on the order of the atoms in the =
original PDB file.

Thus, my questions are:
 - am I wrong in any of the above statements?
 - is there any way to bring to structures of small molecules to a =
"common denominator" that will enable reliable analysis of the 3D =
structure changes?
  - all the files originate from the PDB. Are there internal standards =
that enable unattended creation of Z-matrices?

Assumptions:
 - only chemically identical structures are compared.
 - all the structures will be downloaded from the PDB


Thank you


From owner-chemistry@ccl.net Wed May 28 10:34:00 2008
From: "andras.borosy#%#givaudan.com" <owner-chemistry{=}server.ccl.net>
To: CCL
Subject: CCL: activation energy barriers of DA cycloadditons in organic solvents catalysed by Lewis acids?
Message-Id: <-37053-080528092546-15700-9blRTthdKrhL5CmIgEtDLQ{=}server.ccl.net>
X-Original-From: andras.borosy*givaudan.com
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Date: Wed, 28 May 2008 14:16:22 +0200
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Sent to CCL by: andras.borosy-.-givaudan.com
This is a multipart message in MIME format.
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Dear Colleagues,

Where can I find reliable experimental (or calculated)  activation energy=20
barriers of DA cycloadditons  in organic solvents catalysed by Lewis=20
acids?

Many thank,

Dr. Andr=E1s P=E9ter Borosy
Scientific Modelling Expert
Fragrance Research
Givaudan Schweiz AG  -  Ueberlandstrasse 138  -  CH-8600  -  D=FCbendorf  -=
=20
Switzerland
T:+41-44-824 2164  -  F:+41-44-8242926    -  http://www.givaudan.com
--=_alternative 00436AD4C1257457_=
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<br><font size=3D2 face=3D"sans-serif">Dear Colleagues,</font>
<br>
<br><font size=3D2 face=3D"sans-serif">Where can I find reliable experiment=
al
(or calculated) &nbsp;activation energy barriers of DA cycloadditons &nbsp;=
in
organic solvents catalysed by Lewis acids?</font>
<br>
<br><font size=3D2 face=3D"sans-serif">Many thank,</font>
<br>
<br><font size=3D2 face=3D"sans-serif">Dr. Andr=E1s P=E9ter Borosy<br>
Scientific Modelling Expert<br>
Fragrance Research<br>
Givaudan Schweiz AG &nbsp;- &nbsp;Ueberlandstrasse 138 &nbsp;- &nbsp;CH-8600
&nbsp;- &nbsp;D=FCbendorf &nbsp;- &nbsp;Switzerland<br>
T:+41-44-824 2164 &nbsp;- &nbsp;F:+41-44-8242926 &nbsp; &nbsp;- &nbsp;http:=
//www.givaudan.com</font>
--=_alternative 00436AD4C1257457_=--


From owner-chemistry@ccl.net Wed May 28 11:30:01 2008
From: "Maxim Kholin maxim.kholin[-]q-pharm.com" <owner-chemistry[-]server.ccl.net>
To: CCL
Subject: CCL: Which Drug Design s/w to be Bought for Academic Research
Message-Id: <-37054-080528112101-25627-yiqhJmvx8LTZodidpisMeg[-]server.ccl.net>
X-Original-From: "Maxim Kholin" <maxim.kholin(a)q-pharm.com>
Content-Type: multipart/alternative;
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Date: Wed, 28 May 2008 18:21:48 +0400
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Sent to CCL by: "Maxim Kholin" [maxim.kholin/./q-pharm.com]
This is a multi-part message in MIME format.

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Dear Dr. Wanare,
Let me suggest you looking at www.q-lead.com where Quantum software =
modules are described.
The most of the areas of your interest is covered. Speical Academia =
terms are available.
In many terms the Quantum software is unique using new generation =
approaches.

Maxim Kholin


  ----- Original Message -----=20
  From: gajuguard-ccl{:}yahoo.co.in=20
  To: Kholin, Maxim N =20
  Sent: Tuesday, May 27, 2008 4:51 PM
  Subject: CCL: Which Drug Design s/w to be Bought for Academic Research


        Respected Sir / Madam,

        Our's is the Pharmacy Dept in the SGSITS, an Autonomous =
Institute in MP, INDIA.
        We are in process to buy a drug design software for the purpose =
of doing basic research in drug design (non-profit purpose) for
        - QSAR
        - Docking=20
        - Pharmacophore modeling
        - prediction of ADME parameters=20
        - & other accessories

        So, we are in search of a drug design software to be bought in =
thedept't which is economic, with out time limitation, with neccessary =
accurary & predictability in results for academic research.

        Kindly have some suggestions.

        Thanking you.

        Sincerely,
        Gajanan Wanare,
        Dept't of Pharmacy,
        Shri G S Institute of Technology & Science (SGSITS),
        Indore- (MP) INDIA.
        www.sgsits.ac.in
        gajuguard-ccl(_)yahoo.co.in=20


-------------------------------------------------------------------------=
-----
  Best Jokes, Best Friends, Best Food. Get all this and more on Best of =
Yahoo! Groups.
------=_NextPart_000_04D9_01C8C0EF.B1163B00
Content-Type: text/html;
	charset="UTF-8"
Content-Transfer-Encoding: quoted-printable

=EF=BB=BF<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META http-equiv=3DContent-Type content=3D"text/html; charset=3Dutf-8">
<META content=3D"MSHTML 6.00.2900.2180" name=3DGENERATOR>
<STYLE></STYLE>
</HEAD>
<BODY bgColor=3D#ffffff>
<DIV><FONT face=3DArial size=3D2>Dear Dr. Wanare,</FONT></DIV>
<DIV><FONT face=3DArial size=3D2>Let me suggest you looking at <A=20
href=3D"http://www.q-lead.com">www.q-lead.com</A>&nbsp;where Quantum =
software=20
modules are described.</FONT></DIV>
<DIV><FONT face=3DArial size=3D2>The most of the areas of your interest =
is covered.=20
Speical Academia terms are available.</FONT></DIV>
<DIV><FONT face=3DArial size=3D2>In many terms the Quantum software is =
unique using=20
new generation approaches.</FONT></DIV>
<DIV><FONT face=3DArial size=3D2></FONT>&nbsp;</DIV>
<DIV><FONT face=3DArial size=3D2>Maxim Kholin</FONT></DIV>
<DIV>&nbsp;</DIV>
<DIV><FONT face=3DArial size=3D2></FONT>&nbsp;</DIV>
<BLOCKQUOTE=20
style=3D"PADDING-RIGHT: 0px; PADDING-LEFT: 5px; MARGIN-LEFT: 5px; =
BORDER-LEFT: #000000 2px solid; MARGIN-RIGHT: 0px">
  <DIV style=3D"FONT: 10pt arial">----- Original Message ----- </DIV>
  <DIV=20
  style=3D"BACKGROUND: #e4e4e4; FONT: 10pt arial; font-color: =
black"><B>From:</B>=20
  <A title=3Downer-chemistry]=[ccl.net=20
  =
href=3D"mailto:owner-chemistry]=[ccl.net">gajuguard-ccl{:}yahoo.co.in</A> =
</DIV>
  <DIV style=3D"FONT: 10pt arial"><B>To:</B> <A =
title=3Dmaxim.kholin]=[q-pharm.com=20
  href=3D"mailto:maxim.kholin]=[q-pharm.com">Kholin, Maxim N </A> =
</DIV>
  <DIV style=3D"FONT: 10pt arial"><B>Sent:</B> Tuesday, May 27, 2008 =
4:51 PM</DIV>
  <DIV style=3D"FONT: 10pt arial"><B>Subject:</B> CCL: Which Drug Design =
s/w to be=20
  Bought for Academic Research</DIV>
  <DIV><BR></DIV>
  <TABLE=20
  style=3D"FONT-SIZE: 10pt; WIDTH: 100%; COLOR: #000000; FONT-FAMILY: =
arial; BACKGROUND-COLOR: #ffffff"=20
  cellSpacing=3D0 cellPadding=3D0 background=3Dnone border=3D0>
    <TBODY>
    <TR>
      <TD vAlign=3Dtop>
        <DIV>Respected Sir / Madam,</DIV>
        <DIV>&nbsp;</DIV>
        <DIV>Our's is the Pharmacy Dept in the SGSITS, an Autonomous =
Institute=20
        in MP, INDIA.</DIV>
        <DIV>We are in process to buy a drug design software for the =
purpose of=20
        doing basic research in drug design (non-profit purpose) =
for</DIV>
        <DIV>- QSAR</DIV>
        <DIV>- Docking </DIV>
        <DIV>-&nbsp;Pharmacophore modeling</DIV>
        <DIV>- prediction of ADME parameters </DIV>
        <DIV>- &amp; other accessories</DIV>
        <DIV>&nbsp;</DIV>
        <DIV>So, we are in search of a drug design software to be bought =
in=20
        thedept't&nbsp;which is economic, with out&nbsp;time limitation, =
with=20
        neccessary accurary &amp; predictability in results for academic =

        research.</DIV>
        <DIV>&nbsp;</DIV>
        <DIV>Kindly have some suggestions.</DIV>
        <DIV>&nbsp;</DIV>
        <DIV>Thanking you.</DIV>
        <DIV>&nbsp;</DIV>
        <DIV>Sincerely,</DIV>
        <DIV>Gajanan Wanare,</DIV>
        <DIV>Dept't of Pharmacy,</DIV>
        <DIV>Shri G S Institute of Technology &amp; Science =
(SGSITS),</DIV>
        <DIV>Indore- (MP) INDIA.</DIV>
        <DIV><A =
href=3D"http://www.sgsits.ac.in/">www.sgsits.ac.in</A></DIV>
        <DIV><A=20
        =
href=3D"mailto:gajuguard-ccl(_)yahoo.co.in">gajuguard-ccl(_)yahoo.co.in</=
A></DIV></TD></TR></TBODY></TABLE><BR><!--11-->
  <HR SIZE=3D1>
  </HR>Best Jokes, Best Friends, Best Food. Get all this and more on <A=20
  =
href=3D"http://in.rd.yahoo.com/tagline_groups_11/*http://in.promos.yahoo.=
com/groups/bestofyahoo/">Best=20
  of Yahoo! Groups.</A></BLOCKQUOTE></BODY></HTML>

------=_NextPart_000_04D9_01C8C0EF.B1163B00--


From owner-chemistry@ccl.net Wed May 28 12:04:00 2008
From: "Zsolt Zsoldos zsolt _ simbiosys.ca" <owner-chemistry~!~server.ccl.net>
To: CCL
Subject: CCL: Floating Point Math Errors
Message-Id: <-37055-080528113800-2596-BCOM5bCjPFQzp5iPbhqvmQ~!~server.ccl.net>
X-Original-From: "Zsolt Zsoldos" <zsolt^^simbiosys.ca>
Content-Disposition: inline
Content-Transfer-Encoding: 7bit
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Date: Wed, 28 May 2008 10:40:23 -0400
MIME-Version: 1.0


Sent to CCL by: "Zsolt Zsoldos" [zsolt{=}simbiosys.ca]
Hello,

The short answer is: fixed point representation can help to eliminate
floating point errors in some cases, but not for the case of rotation.
I have put a detailed explanation to answer this question on my blog
with some example code as well. It is too long to post here, so I only
include the URL:
http://www.simbiosys.ca/blog/

Zsolt

> Sent to CCL by: "Sina  T  reli" [sinatureli%a%gmail.com]
> Hello,
>
> I am working on a project related to proteins and my precision for coordinates
> is there digits after the dot. When I do operations like rotation around a
> dihedral, the dihedrals which shouldn't change change at about 0.01 angles
> and so. I am afraid though that is not much it might accumulate over time. So
> do you have any suggestions for reducing floating integer errors? Would't be
> feasible if I turned lets say the coordinate 21.567 to 21567 and do my
> operations? Or maybe even 215670?
>

--
Zsolt Zsoldos, PhD    http://www.simbiosys.ca/


From owner-chemistry@ccl.net Wed May 28 15:15:00 2008
From: "=?ISO-8859-1?Q?Sina_T=FCreli?= sinatureli.:.gmail.com" <owner-chemistry#server.ccl.net>
To: CCL
Subject: CCL: Floating Point Math Errors
Message-Id: <-37056-080528151225-8144-6zc0y7WygBR78CT8N6bbCQ#server.ccl.net>
X-Original-From: "=?ISO-8859-1?Q?Sina_T=FCreli?=" <sinatureli.:.gmail.com>
Content-Type: multipart/alternative; 
	boundary="----=_Part_32984_20562670.1212001905355"
Date: Wed, 28 May 2008 22:11:45 +0300
MIME-Version: 1.0


Sent to CCL by: "=?ISO-8859-1?Q?Sina_T=FCreli?=" [sinatureli**gmail.com]
------=_Part_32984_20562670.1212001905355
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Content-Transfer-Encoding: 7bit
Content-Disposition: inline

Thanks for the answer

On Wed, May 28, 2008 at 5:40 PM, Zsolt Zsoldos zsolt _ simbiosys.ca <
owner-chemistry-.-ccl.net> wrote:

>
> Sent to CCL by: "Zsolt Zsoldos" [zsolt{=}simbiosys.ca]
> Hello,
>
> The short answer is: fixed point representation can help to eliminate
> floating point errors in some cases, but not for the case of rotation.
> I have put a detailed explanation to answer this question on my blog
> with some example code as well. It is too long to post here, so I only
> include the URL:
> http://www.simbiosys.ca/blog/
>
> Zsolt
>
> > Sent to CCL by: "Sina  T  reli" [sinatureli%a%gmail.com]
> > Hello,
> >
> > I am working on a project related to proteins and my precision for
> coordinates
> > is there digits after the dot. When I do operations like rotation around
> a
> > dihedral, the dihedrals which shouldn't change change at about 0.01
> angles
> > and so. I am afraid though that is not much it might accumulate over
> time. So
> > do you have any suggestions for reducing floating integer errors? Would't
> be
> > feasible if I turned lets say the coordinate 21.567 to 21567 and do my
> > operations? Or maybe even 215670?
> >
>
> --
> Zsolt Zsoldos, PhD    http://www.simbiosys.ca/>
>
>


-- 
"Vectors have never been of the slightest use to any creature. Quaternions
came from Hamilton after his really good work had been done; and though
beautifully ingenious, have been an unmixed evil to those who have touched
them in any way, including Maxwell." - Lord Kelvin

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Thanks for the answer<br><br>
<div class="gmail_quote">On Wed, May 28, 2008 at 5:40 PM, Zsolt Zsoldos zsolt _ <a href="http://simbiosys.ca">simbiosys.ca</a> &lt;<a href="mailto:owner-chemistry-.-ccl.net">owner-chemistry-.-ccl.net</a>&gt; wrote:<br>
<blockquote class="gmail_quote" style="PADDING-LEFT: 1ex; MARGIN: 0px 0px 0px 0.8ex; BORDER-LEFT: #ccc 1px solid"><br>Sent to CCL by: &quot;Zsolt Zsoldos&quot; [zsolt{=}<a href="http://simbiosys.ca/" target="_blank">simbiosys.ca</a>]<br>
Hello,<br><br>The short answer is: fixed point representation can help to eliminate<br>floating point errors in some cases, but not for the case of rotation.<br>I have put a detailed explanation to answer this question on my blog<br>
with some example code as well. It is too long to post here, so I only<br>include the URL:<br><a href="http://www.simbiosys.ca/blog/" target="_blank">http://www.simbiosys.ca/blog/</a><br><br>Zsolt<br>
<div class="Ih2E3d"><br>&gt; Sent to CCL by: &quot;Sina &nbsp;T &nbsp;reli&quot; [sinatureli%a%<a href="http://gmail.com/" target="_blank">gmail.com</a>]<br>&gt; Hello,<br>&gt;<br>&gt; I am working on a project related to proteins and my precision for coordinates<br>
&gt; is there digits after the dot. When I do operations like rotation around a<br>&gt; dihedral, the dihedrals which shouldn&#39;t change change at about 0.01 angles<br>&gt; and so. I am afraid though that is not much it might accumulate over time. So<br>
&gt; do you have any suggestions for reducing floating integer errors? Would&#39;t be<br>&gt; feasible if I turned lets say the coordinate 21.567 to 21567 and do my<br>&gt; operations? Or maybe even 215670?<br>&gt;<br><br>
</div><font color="#888888">--<br>Zsolt Zsoldos, PhD &nbsp; &nbsp;<a href="http://www.simbiosys.ca/" target="_blank">http://www.simbiosys.ca/</a><br></font>
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