Subject: Poly-Ala

From: Shaun Black <[email-masked]>
Date: Fri, 14 Jun 91 18:34:31 EST

It is my recollection that poly-Ala is only sparingly soluble in water,
but enough can be gotten into solution to do a CD spectrum and see that it
is alpha helical.  Poly-Gly will probably be more soluble in water, but
only because it likely unfolds and hydrogen bonds with the solvent.  My
bet is for "random coil" in water.  It's not clear to me what the entropic
considerations would be, net.  More discussion on this would be interesting.

=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=
Shaun D. Black          | Bitnet: [email-masked]
Ohio State University   | Internet: [email-masked]
College of Pharmacy     | Phone: (614) 292-3925
500 West 12th Avenue    | FAX:   (614) 292-2435
Columbus, OH 43210-1291 | :-)
=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=