Subject: Modelling hydrophobic interactions

From: [email-masked] (Hr Dr. S. Shapiro)
Date: Fri, 3 Jun 1994 11:11:11 +0100 (MEST)

Dear colleagues;

     I am interested in examining the interactions between biological mem-
branes and hydrophobic weak acids in order to better understand why some of
these acids are toxic towards cells and others are not.  The molecular
modelling software I have at my immediate disposal are Hyperchem 3.0 and
MOPAC 6.0.  Can anyone suggest how these programmes might be used to examine
prospective interactions between biomembranes and small molecular weight com-
pounds?  Would anyone care to recommend _other_ programmes which can be used
to accomplish this?

     Thanks in advance to all respondents.

                                            Sincerely,

                                            S. Shapiro
                                            Internet: [email-masked]

P.-S.: Of course, references and citations are also useful.