Subject: logP

From: Frederic Billois <[email-masked]>
Date: Tue, 13 Feb 1996 14:48:18 +0100

Created, developed and extensively tested at the Institute of 
Medicinal Chemistry of the University of Lausanne , CLIP is
a package with the following capabilities: 

Computation and representation of the Molecular Lipophilicity Potential (MLP) 
on the solvent-accessible surface of molecules and macromolecules; 
Calculation of n-octanol/water partition coefficients (log Poct) from the MLP
on the solvent-accessible surface; 
Calculation of virtual log P values for individual conformers, and exploration
of the lipophilicity range accessible to a compound; 
Computation and representation of the MLP in a given region of space around
molecules and macromolecules; 
Computation and incorporation of the MLP into Comparative Molecular Field 
Analysis (CoMFA)©. 

Information about CLIP, publications can be found on the web at:

                                        http://www.unil.ch/pharm/clip/
--------------------------------------------------------------
Frederic Billois
Universite de Lausanne
Section de Pharmacie.
Institut de Chimie Therapeutique.
CH-1015 Dorigny-Lausanne
Suisse
Tel :+41.21.692.45.24     
Fax :+41.21.692.45.05
Internet:  [email-masked]
WWW : http://www.unil.ch/pharm/ict/docs/ict.html
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