Subject: geom. optimiz. of macrolide

From: [email-masked] (Nathalie Vancampenhout K136.4.96)
Date: Thu, 14 Aug 1997 12:07:47 +0200

Dear all,
I am trying to optimiza the geometry of a macrolide with the s-e method AM1.
The geometry doesn't reach a convergence...Is there someone with any
experience with such of problem?
Thanks for helpinf
Nathalie