Subject: TRIPOS LEAPFROG !

From: Richard M Day <[email-masked]>
Date: Thu, 19 Nov 1998 08:41:26 +0000

Dear All,

I am trying to find people with experience in using LEAPFROG to suggest
lead affinity peptides.  

The big question - does this work at all ?? 

What is is the best way of sifting out the definate non-running peptides
before synthesis ? 

Is it worth seeing if one of the low energy conformations of the peptide is
close to the one required to provide interaction with the binding site -
i.e the one suggested by the lead finding program.

Your Comments would be greatfuly appreciated,

Thanks

Richard D.
Cranfield University
MK43 0AL

+44 (0)468 582085