Subject: need tough distance geometry problems

From: "Dimitris K. Agrafiotis" <[email-masked]>
Date: Mon, 25 Jan 1999 08:42:48 -0600

Dear CCL members,

I am looking for the toughest structure determination
problems known in the literature that involve the
generation of atomic coordinates from distance
constraints. That would include NMR problems,
protein folding and threading, conformational
searching, and things of that nature. Of particular
interest are problems with missing, noisy or corrupt
data, and problems that are considered intractable
with current techniques. Your help would be GREATLY
appreciated. 

Thanks,

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Dimitris K. Agrafiotis, PhD              | E-mail: [email-masked]
3-Dimensional Pharmaceuticals, Inc.      | Tel:    (610) 458-6045
665 Stockton Drive, Suite 104            | Fax:    (610) 458-8249
Exton, PA 19341