Subject: hydrodynamic properties from structures?

From: Bruce Allan Palfey <[email-masked]>
Date: Mon, 6 Dec 1999 15:48:32 -0500 (EST)

In the "old" days of biophysics, when 3-D structures were still fairly
hard to come by, people would get very rough ideas of the shape of
proteins from hydrodynamic experiments like analytical ultracentrifugation
or viscosity measurements.  I was wondering if things have now come full
circle:  Given a protein structure from crystallography or NMR, are there
any programs that will calculate the frictional coefficient or shape
parameters used in hydrodynamic analyses?

Thanks in advance,

Bruce Palfey
Department of Biological Chemistry
University of Michigan
Ann Arbor, MI 48109-0606