Subject: Re: CCL:experiment of H-bond strength in solution

From: Adrian Mulholland <[email-masked]>
Date: Thu, 22 Mar 2001 09:39:20 +0000 (GMT)

Dan Herschlag has done some interesting experimental work 
on H-bonds in solution, see e.g.

Shan, S., Loh, S., Herschlag, D. 'The Energetics of 
Hydrogen Bonds in Model Systems: Implications for Enzymatic 
Catalysis', Science 272, 97-101 (1996)

Shan, S., Herschlag, D. 'The change in hydrogen bond 
strength accompanying charge rearrangement: Implications 
for enzymatic catalysis' Proc. Natl. Acad. Sci. USA 93, 
14474-14479 (1996)

Shan, S., Herschlag, D. 'Energetic Effects of Multiple 
Hydrogen Bonds. Implications for Enzymatic Catalysis', 
J.Am.Chem.Soc. 118, 5515-5518

Shan, S. and Herschlag, D. (1998) 'Hydrogen Bonding in 
Enzymatic Catalysis: Analysis of Energetic Contributions.' 
In Methods in Enzymology , Vol. 308, Schramm, V.L. and 
Purich, D.L., eds. Academic Press, San Diego, pp. 246-276.

Adrian
----------------------
Adrian Mulholland

School of Chemistry        Phone: 0117-928-9097
University of Bristol      Fax:   0117-925-1295
Bristol BS8 1TS            [email-masked]