Subject: Call for Papers: Predictive ADME/Predictive Toxicology (fwd)

From: Jan Labanowski <[email-masked]>
Date: Sat, 29 Mar 2003 01:09:13 -0500 (EST)

---------- Forwarded message ----------
Date: Fri, 28 Mar 2003 15:06:53 -0500
From: Jennifer Laakso <[email-masked]>
To: Jkl <[email-masked]>
Subject: Call for Papers: Predictive ADME/Predictive Toxicology

FIRST ANNOUNCEMENT AND CALL FOR PAPERS
Cambridge Healthtech Institute Presents
Predictive ADME
November 17-18, 2003    Predictive Toxicology
November 19-20, 2003

Improving Lead Selection Through Innovative Thinking
Boston Park Plaza | Boston, MA

With 50% of drug failures attributed to ADME-Tox issues, it is critical to accurately predict these qualities earlier
in the investigation of a lead to assure appropriate attrition from the drug development process. Empirical assays
have been the mainstay of evaluating ADME and toxicity, but they suffer from low throughput and difficulty to automate.
New techniques and technologies for predicting these qualities must become more accurate and have the ability to
be validated against empirical findings. It will then be possible to drop compounds that are most likely to exhibit
ADME or tox problems sooner, and provide ways for researchers to arrive at the same conclusions, but in less time.
The more attractive compounds can then be put on the development fast-track.
These two, 1.5 day, back-to-back meetings will provide a forum for discussion of new techniques, technologies, and
strategies that hold promise for improving the selection of potent, on-target leads with fewer negative side-effects,
thus saving time and money. Researchers with experience in applying new technologies or techniques are en-
couraged to submit a proposal for oral presentation at one of the two meetings.
Topics may include, but are not limited to:
Correlation of predictive with empirical results
Innovative algorithms
Modeling and/or profiling
Reliable databases-searching, building
Building neural networks for predictive ADMET
Gene expression analysis
Structure-based prediction
Combination technologies/techniques
Standardization of profiling data format
Case studies of empirical assay replacement
Combining "-omics" profiling data
Novel Descriptors for Compounds
Expression profiles to understand mode of toxicity
Researchers who would like to be considered for oral presentations, or to display a poster, are encouraged to
submit a title and 3-5 sentence summary of your data, suitable for use in the program brochure should your abstract
be selected for oral presentation. Please include full contact information for the presenter. Proposals are subject to
review by the Scientific Advisory Board.
Are there specific topics or speakers in this area that you would like included in this meeting? If so, please send those
suggestions along to help give you the information you need to better meet your research goals.

To submit proposals on-line: click here

Deadline for Submissions: April 11, 2003
For more information, please contact:
Elizabeth Lamb, Conference Director, Cambridge Healthtech Institute
Fax: 207-493-4573, E-mail: [email-masked]
For sponsorship or exhibitor information, contact:
Angela Parsons, email: [email-masked] or tel: 617-630-1367.

If the above information is not of interest to you, please disregard and we apologize for any inconvenience this may have caused.
To be removed from further emails, click here or contact Audrey Morrissey at [email-masked] or 617-630-1348.