Subject: MolIDE -- an open-source graphical environment for homology modeling

From: Roland Dunbrack <Roland.Dunbrack |a| fccc.edu>
Date: Wed, 18 May 2005 16:18:54 -0400

We would like to introduce MolIDE,  an open-source cross-platform  
graphical environment for homology modeling. It implements the most  
frequently used steps involved in basic homology modeling:
	
-- multiple-round PSI-BLAST search of the non-redundant sequence  
database
-- secondary structure prediction based on PSI-BLAST results with  
PSIPRED
-- PSI-BLAST of PDB sequences with profiles generated in search of  
non-redundant database
-- sortable table of PDB results to aid selection of templates for  
homology modeling
-- assisted alignment editing, integrating a template structure viewer  
and secondary structure prediction
-- model construction, including handling of SEQRES/coordinate residue  
numbering issues
-- side-chain replacement with SCWRL
-- loop building, with visually-assisted selection of anchor residues

MolIDE is currently available for Windows and Linux.
The program is freely available to both non-profit and commercial users.
More information is available on this site:

	http://dunbrack.fccc.edu/molide

The paper is available online:

	http://www.ncbi.nlm.nih.gov/entrez/query.fcgi? 
cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845657

Adrian Canutescu and Roland Dunbrack

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* Roland L. Dunbrack, Jr.
* Member
* Institute for Cancer Research
* Fox Chase Cancer Center
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* Roland.Dunbrack @ fccc.edu
* http://dunbrack.fccc.edu (research)
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