From owner-chemistry@ccl.net Mon Apr 25 10:53:00 2022
From: "Norrby, Per-Ola Per-Ola.Norrby\a/astrazeneca.com" <owner-chemistry|-|server.ccl.net>
To: CCL
Subject: CCL: How to eliminate the spin contamination in the ORCA
Message-Id: <-54647-220425015915-1054-9hPHMW+QA8/i/01J/WeMKw|-|server.ccl.net>
X-Original-From: "Norrby, Per-Ola" <Per-Ola.Norrby%%astrazeneca.com>
Content-Language: en-US
Content-Type: multipart/alternative;
	boundary="_000_PA4PR04MB96375F9031685373847BD856CAF89PA4PR04MB9637eurp_"
Date: Mon, 25 Apr 2022 05:59:01 +0000
MIME-Version: 1.0


Sent to CCL by: "Norrby, Per-Ola" [Per-Ola.Norrby,+,astrazeneca.com]
--_000_PA4PR04MB96375F9031685373847BD856CAF89PA4PR04MB9637eurp_
Content-Type: text/plain; charset=UTF-8
Content-Transfer-Encoding: base64
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--_000_PA4PR04MB96375F9031685373847BD856CAF89PA4PR04MB9637eurp_
Content-Type: text/html; charset=UTF-8
Content-Transfer-Encoding: base64
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--_000_PA4PR04MB96375F9031685373847BD856CAF89PA4PR04MB9637eurp_--