From sling@euclid.chem.washington.edu  Sat Jul 30 05:12:32 1994
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          id AA23034; Fri, 29 Jul 1994 21:58:50 -0700
Date: Fri, 29 Jul 1994 21:58:50 -0700
From: sling@euclid.chem.washington.edu (Song Ling)
Message-Id: <9407300458.AA23034@euclid.chem.washington.edu>
To: CHEMISTRY@ccl.net
Subject: BIOSYM's Huai Sun's address


Someone earlier today asked for Huai Sun's e-mail address (saying that
Sun helped put some program/software together), I have Sun's address 
as follows:
huai@iris40.biosym.com or huai@ibm14.biosym.com.

From eslone@mason1.gmu.edu  Sat Jul 30 16:12:41 1994
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	id AA01060; Sat, 30 Jul 1994 11:31:21 -0400
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Subject: ACS Meeting Announcement
To: chemistry@ccl.net
Date: Sat, 30 Jul 1994 11:31:20 -0400 (EDT)
From: "J. Eric Slone" <eslone@mason1.gmu.edu>
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                MEETING ANNOUNCEMENT

ENVIRONMENTALLY BENIGN SYNTHESES AND PROCESSES IN THE
                CHEMISTRY CURRICULUM


  	A joint effort between the US Environmental
Protection Agency (EPA) and the National Science Foundation
(NSF) has been initiated recently to promote the inclusion of
pollution prevention issues (in particular, Benign By Design
Chemistry including Alternative Synthetic Pathways) in college
and graduate level chemistry curricula.  A one-day session to
present and discuss the current status and future of this
concept with key individuals from the scientific community is
planned.  The session will consist of three quarters of a day of
formal talks followed by a quarter-day roundtable discussion. 
The venue is the American Chemical Society National Meeting in
Washington, DC and the date is August 21st, 1994.  Key
participants at the session will include chemistry textbook
authors, college and university professors involved in
alternative synthesis research, industry representatives, and
EPA and NSF representatives.

The session outline is provided below.


Environmentally Benign Syntheses and Processes in the
Chemistry Curriculum

A Session of the "Design for the Environment" Symposium 
Sponsored by the Division of Environmental Chemistry 
Co-Listed with the Division of Chemical Education
208th National Meeting of the American Chemical Society
Washington, DC  *  August 21, 1994


MORNING SESSION  (Margaret Cavanaugh presiding)


	INTRODUCTORY REMARKS

	 Margaret Cavanaugh, National Science Foundation



	Incorporating Alternative Synthetic Pathway Design
Into The Synthetic Chemistry Curriculum: EPA Perspectives

	 Tracy C. Williamson and Paul T. Anastas,
Environmental Protection Agency



	Making A Place For Environmentally Benign Synthesis
In The Introductory Chemistry Curriculum: Is It A Moral
Imperative?

	 Frank Vellaccio, College of the Holy Cross



	Environmentally Benign Synthesis In The Introductory
Organic Chemistry Lecture Course

	 Francis A. Carey and Andrew F. Carey, University of
Virginia



	Incorporating Environmental Issues Into The
Inorganic Chemistry Curriculum

	 James E. Huheey, University of Maryland

	Integrating Environmental Chemistry Into
Introductory Chemistry For Majors And Non-majors

	 William C. Trogler, John D. Simon, and Harry Gray,
University of California at San Diego



	SYNGEN Program For Teaching Alternative Syntheses

	 James B. Hendrickson, Brandeis University 



	Incorporating Pollution Prevention Into The
Chemistry Curriculum: New Challenges And Opportunities

	 Gregory A. Keoleian and Jonathan W. Bulkley,
University of Michigan 



	Graduate Research And Training In Chemistry Of The
Environment At M.I.T.

	 Jeffrey I. Steinfeld and David S. Bem,
Massachusetts Institute of Technology



AFTERNOON SESSION (Tracy Williamson presiding)



	Pollution Prevention In The Organic And Inorganic
Chemistry Laboratory: Microscale Approach

	 Mono M. Singh, Ronald M. Pike, and Zvi Szafran,
National Microscale Chemistry Center/Merrimack College



	Securing Environmental Concerns in the Chemistry
Curriculum

	 Leverett R. Smith, Merritt College



	A Company Program To Introduce Pollution Prevention
(P2) Concepts Into Chemical Process Development

	 Michael J. Wallace, Sandoz Pharmaceutical
Corporation



	Environmental Education From An Industrial
Perspective

	 John C. Tully, Bell Labs



	PANEL DISCUSSION: The Future Of Environmentally
Benign Syntheses And Processes In The Chemistry Curriculum

	 Paul Anastas, Environmental Protection Agency (facilitator)



	CLOSING REMARKS

	 Paul Anastas, Environmental Protection Agency


* For more information, contact session chairs

Paul Anastas
Office of Pollution Prevention and Toxics
U.S. Environmental Protection Agency
Washington, DC 20460
(202) 260-2257


Tracy Williamson
Office of Pollution Prevention and Toxics
U.S. Environmental Protection Agency
Washington, DC 20460
(202) 260-3960


Margaret Cavanaugh
Division of Chemistry
National Science Foundation
Arlington, VA 22230
(703) 306-1842




From eslone@mason1.gmu.edu  Sat Jul 30 16:29:58 1994
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Subject: ACS Meeting Announcement
To: chemistry@ccl.net
Date: Sat, 30 Jul 1994 11:30:54 -0400 (EDT)
From: "J. Eric Slone" <eslone@mason1.gmu.edu>
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IMPORTANT MEETING ANNOUNCEMENT


Designing Safer Chemicals


	The United States Environmental Protection Agency
(EPA) is hosting two sessions (morning and afternoon) entitled
Designing Safer Chemicals (these sessions are part of the
week-long ACS Symposium "Design for the Environment: The
Environmental Paradigm for the Twenty-first Century", sponsored
by the ACS Division of Environmental Chemistry, ACS National
Meeting, to be held in Washington DC, August 21-25, 1994).  The
Designing Safer Chemicals sessions are devoted to the concept of
utilizing medicinal chemistry principles for the design of less
toxic industrial chemicals, and will be held on Thursday, August
25, 1994 at the Washington D.C. Convention Center.  The purpose
of the Designing Safer Chemicals sessions are to: 


	1) 	stimulate chemical companies to: consider the
structural tradeoffs between efficacy and toxicity of chemicals
before they are made; consider the structural alteration of
existing chemicals to reduce toxicity while maintaining
efficacy; and to minimize toxicity whenever possible through
rational chemical design;

	2) 	stimulate academicians to consider basic
research in toxicological mechanisms that may lead to the
design of less toxic chemicals;

and 

	3) 	stimulate funding institutions to consider
funding academic research in the area of toxicological
mechanisms which could lead to the design of less toxic
chemicals. 


	Topics that will be covered by recognized experts
during the sessions include: toxic mechanisms; controlling
bioactivation; retrometabolic concepts; isosteric replacement;
controlling bioavailability; examples of functional groups or
chemicals of particular concern to EPA; and specific examples of
how safer chemicals have been designed by commercial
manufacturers.  The Designing Safer Chemicals sessions format
and speakers are presented below.  



For additional information contact:

 

	Dr. Stephen C. DeVito, US EPA, phone: 202-260-1748,
	FAX 202-260-1661, 

	E-Mail devito.stephen@epamail.epa.gov  	
or 
	Dr. Roger L. Garrett, US EPA, phone 202-260-4302, 
	FAX 202-260-1279



ACS SESSIONS*



"DESIGNING SAFER CHEMICALS"


Thursday, August 25, 1994
ACS National Meeting 
Washington D.C. Convention Center
Washington, D.C.


Two chemistry sessions devoted to the concept of
utilizing medicinal  chemistry principles for the design of less
toxic industrial chemicals. 


Sessions Format and Speakers:


Morning Session

Designing Safer Chemicals: A New Approach To
Pollution Prevention

Roger L. Garrett, U.S. Environmental Protection
Agency, Washington, DC 


General Principles for the Design of Safer Chemicals

Stephen C. DeVito, U.S. Environmental Protection
Agency, Washington, DC 


Designing Safer Chemicals: Role of Bioactivation in
Chemical Toxicity 

Marion Anders, Univ. Rochester, NY 


Predicting Rates of Bioactivation by Cytochrome
P-450, and its Application to the Design of Safe Chemicals

Jeffrey Jones, Univ. Rochester, NY 


A Biochemical Based Approach for Designing Safer
Nitriles

Stephen C. DeVito, U.S. Environmental Protection
Agency, Washington, DC 


Structure-Activity Relationships of Haloalkanes

Marion Anders, Univ. Rochester, NY 


Design of Biologically Safer Chemicals Based on
Retrometabolic Concepts

Nicholas Bodor, Univ. Florida, FL

 

Afternoon Session



Isosteric Replacement in the Design of Safer
Chemicals 

Scott Sieburth, Stony Brook Univ., NY 


Use of Computers in Toxicology

George W.A. Milne, National Cancer Institutes, NIH,
Bethesda, MD


Designing an Environmentally Safe Marine Antifoulant

G.L. Willingham, and A. Jacobson, Rohm and Haas
Company, Spring House, PA 


Imine-Isocyanate Chemistry: New Technology for High
Solids Coatings

L.D. Venham, D.A. Wicks, P.E. Yeske, ICD Coatings,
Miles Inc., Pittsburgh, PA


Non Isocyanate Sealants

M.F. DePompei, Tremco Inc., Beachwood, OH 


From Customer Focus to Pollution Prevention

J.L. Kostusyk, The Lubrizol Corp., Wickliffe, OH


Emulsion Polymers for the 90's

G.A. Ungefug, Para-Chem Southern, Inc., Simpsonville,
SC

		
"Everybody Wins" Technology 

G. Sugerman, Pi-Tech, Inc., Jersey City, NJ


* Part of the ACS Symposium "Design for the
Environment: The Environmental Paradigm for the Twenty-first
Century", sponsored by the Division of Environmental Chemistry.

For additional information contact: 

Dr. Stephen C. DeVito, US EPA, phone: 202-260-1748,
FAX 202-260-1661, 

	E-Mail devito.stephen@epamail.epa.gov  	or

 

Dr. Roger L. Garrett, US EPA, phone 202-260-4302, 
FAX 202-260-1279


