From chemistry-request@server.ccl.net Fri Dec 17 18:09:31 1999 Received: from saratoga.orconet.com (saratoga.orconet.com [206.66.136.11]) by server.ccl.net (8.8.7/8.8.7) with ESMTP id SAA07492 for ; Fri, 17 Dec 1999 18:09:30 -0500 Received: from molecules.com ([216.98.228.87]) by saratoga.orconet.com (Netscape Messaging Server 3.6) with ESMTP id AAA2E6B for ; Thu, 16 Dec 1999 18:53:30 -0800 Message-ID: <3859A2AC.25429D48@molecules.com> Date: Thu, 16 Dec 1999 18:40:44 -0800 From: James Givens Reply-To: jamesg@molecules.com Organization: Molecular Arts Corporation X-Mailer: Mozilla 4.6 [en] (Win95; I) X-Accept-Language: en MIME-Version: 1.0 To: chemistry@ccl.net Subject: WebMolecules News - Dec 99 Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit A new version of the award-winning site: ** WebMolecules.com ** is now available at http://www.webmolecules.com Visualize molecules in 3D - real-time on the Web - for FREE! New Features: -------------------------------------------------------------- - Improved SEARCH capabilities. You can search the entire WebMolecules Library by formula. Exact matching is used to search the entire database. Partial matching is also used to search our Top 2000. - SEARCH can now accept formula strings in any order. Previously, there was a "CH alpha" order restriction. http://www.webmolecules.com/search.shtml - Another 25,000 CAS-indexed molecular models have been added. We now have over 125,000 molecular models on-site. Search for these by CAS number or exact formula. http://www.webmolecules.com/search.shtml December's Molecule -------------------------------------------------------------- Thalidomide http://www.webmolecules.com/cgi-bin/webmolpage.cgi?thalidmd.m3d Formula: C13H10N2O4 Weight: 258.233(1) g/mol Originally prescribed as a sedative/hypnotic drug to fight morning-sickness in the '50's and '60's. Banned in the early 1960s after causing severe birth defects, mostly in Europe and Canada. The drug was never approved for distribution in the United States. Thalidomide is in a class of drugs called angiogenesis inhibitors. It disrupts growth of blood vessels by attacking the cells that form their walls. Without such vessels, tumors are starved of nutrients and cannot grow. Clinical trials indicate some effectiveness against: advanced multiple myeloma, prostate cancer, and glioblastoma. Second major mechanism of action: blocks overproduction of Tumor Necrosis Factor (TNF), a naturally-occurring inflammatory protein implicated in a number of diseases, such as: Crohn's, rheumatoid arthritis, diabetes, and the inflammatory complications of leprosy. Currently offered as Thalomid(R) by Celgene of Warren, NJ Other Recent WebMolecules.com Upgrades and New Features -------------------------------------------------------------- - Email Models to Friends. Use the Email-a-Model link. - 100's of large macro-structures have been added. - New Visitor Uploads are available in Category 28.0 - Support for both Chime and VRML plug-ins - For performance reasons, large molecules (>150 atoms) are available for the Chime viewer only. - Mirror sites for the VRML plug-ins have been added. See: http://www.webmolecules.com/vrmlint.shtml - Mirror sites for the Chime plug-in has been added. See: http://www.webmolecules.com/chimeint.shtml - Resizable viewing window - Support for uploads and model requests - Improved support for bookmarks - 3D coordinate downloads (M3D, MOL, PDB) -------------------------------------------------------------- WebMolecules.com is a FREE, sponsor-supported site. Designed for the 3D visualization of molecules, it contains over 125,000 molecular structures in 3D. Thousands of common molecules are organized into 30+ categories. Our TOP 2000 includes molecules of commercial value, educational importance, and of topical interest. It is indexed by formula and category and is also fully searchable. Our TOP 2000 molecules include: - Top 100 pollutants - Top 100 commercial chemicals - Top 200 pharmaceuticals - Common valence geometries - Common orbital configurations WebMolecules.com is great for student and classroom use. -------------------------------------------------------------- KNOW SOMEONE WHO MIGHT ENJOY WEBMOLECULES? Feel free to forward WebMolecules News to your colleagues. If you received this issue from a friend and would like to receive information directly, you can join our mailing list by clicking the Free Newsletter link at: http://www.webmolecules.com or better yet, tell them to sign-up directly on: http://www.webmolecules.com/newsletter.shtml -------------------------------------------------------------- Enjoy, -- James Givens ---------------------------------------------------------------- Molecular Arts Corporation | Hanover Corporate Centre, Suite 1000 | http://www.molecules.com 1532 East Katella Avenue | Main: (714) 634-8100 Anaheim, California 92805-6627 USA | FAX: (714) 634-1999 ---------------------------------------------------------------- From chemistry-request@server.ccl.net Sat Dec 18 06:12:05 1999 Received: from mail.rwth-aachen.de (mail.RWTH-Aachen.DE [137.226.144.9]) by server.ccl.net (8.8.7/8.8.7) with ESMTP id GAA02888 for ; Sat, 18 Dec 1999 06:12:04 -0500 Received: from ac.rwth-aachen.de (zosia.dorf.RWTH-Aachen.DE) by mail.rwth-aachen.de (PMDF V5.1-12 #D3869) with ESMTP id <01JJN87NXAQ200037G@mail.rwth-aachen.de> for CHEMISTRY@ccl.net; Sat, 18 Dec 1999 11:09:49 +0100 Date: Sat, 18 Dec 1999 11:07:37 +0100 From: Krzysztof Radacki Subject: nslookup Sender: krzys@mail.rwth-aachen.de To: CCL Message-id: <385B5CE9.1E385389@ac.rwth-aachen.de> Organization: RWTH Aachen MIME-version: 1.0 X-Mailer: Mozilla 4.61 [en] (X11; I; Linux 2.2.12-20 i686) Content-type: text/plain; charset=us-ascii Content-transfer-encoding: 7bit X-Accept-Language: en Hi CCl, I have a small problem a little bit out of chemistry. I want to download last version of visual tcl/tk. It can be found on www.neuron.com but unfortunately all DNS servers here in Aachen answering me that this host is unknown. I'm nearly sure that it's known because I've been there for some weeks/months and actual net-search also pointing me to the same site. So my ask - can somebody in US make for me: nslookup www.neuron.com and send me IP number of this host? regards Krzys Radacki _____________________-------------------------------------------------- --------------------- e-mail: Krys.Radacki@ac.RWTH-Aachen.DE --- ----------------------------------------------------------------------- From chemistry-request@server.ccl.net Sat Dec 18 12:38:22 1999 Received: from deimos.cber.nih.gov (deimos.cber.nih.gov [128.231.52.2]) by server.ccl.net (8.8.7/8.8.7) with ESMTP id MAA02551 for ; Sat, 18 Dec 1999 12:38:22 -0500 Received: from localhost by deimos.cber.nih.gov with SMTP (1.37.109.14/16.2) id AA025594412; Sat, 18 Dec 1999 11:26:52 -0500 Date: Sat, 18 Dec 1999 11:26:52 -0500 (EST) From: Rick Venable To: Krzysztof Radacki Cc: CCL Subject: Re: CCL:nslookup In-Reply-To: <385B5CE9.1E385389@ac.rwth-aachen.de> Message-Id: Mime-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII On Sat, 18 Dec 1999, Krzysztof Radacki wrote: > I have a small problem a little bit out of chemistry. > I want to download last version of visual tcl/tk. It can be > found on www.neuron.com but unfortunately all DNS servers > here in Aachen answering me that this host is unknown. > I'm nearly sure that it's known because I've been there for some > weeks/months and actual net-search also pointing me to the same > site. > So my ask - can somebody in US make for me: > nslookup www.neuron.com > and send me IP number of this host? I couldn't locate that site either-- but take a look at www.tcltk.com I'm sure you'll find pointers to what you're looking for, and quite a bit more. -- Rick Venable =====\ |=| "Eschew Obfuscation" FDA/CBER Biophysics Lab |____/ |=| Bethesda, MD U.S.A. | \ / |=| ( Not an official statement or Rick_Venable@nih.gov | \ / |=| position of the FDA; for that, http://www.erols.com/rvenable \/ |=| see http://www.fda.gov )