From: chemistry-request at ccl.net <br />
To: chemistry-request at ccl.net<br />
Date: Wed Dec 16 09:50:57 2020<br />
Subject: 21.01.13 <span class="fancysmall">Webinar - Exploit prior knowledge: Understand SAR to inform ligand design</span><br />

<pre>
Date: January 13th

Time: 6pm GMT / 1pm EST / 10am PST

Duration: 45 minutes

Format: Webinar

Presenter: Sylvie Sciammetta, Application Scientist

In drug discovery programs, summarizing and understanding the SAR for 
large sets of compounds can be both challenging and time-consuming. 
This webinar will focus on using Forge, the Cresset workbench for 
SAR analysis and molecule design. You will learn how Activity Miner 
and Activity Atlas can give a clear rationale for changes in activity 
and provide inspiration for how to exploit this knowledge in new 
design iterations. Topics covered include finding critical regions 
of activity using activity cliff analysis; understanding the 
electrostatic and shape changes that cause a difference in activity; 
generating meaningful summaries of SAR into a visual 3D model to 
inform molecule design and help prioritize molecules for synthesis.

Find out more and register for free at:
<a href="https://www.cresset-group.com/about/events/SAR-13Jan/" target="_blank">https://www.cresset-group.com/about/events/SAR-13Jan/</a></pre>
<b>NOTE THAT E-MAIL ADDRESSES HAVE BEEN MODIFIED!!!</b><br />
All @ signs were changed to :+: to fight spam. Before you send e-mail, you
need to change :+: to @<br />
For example: change joe:+:big123comp.com to joe@big123comp.com<br />
<em>Please let colleagues know about conference listingts at
Computational Chemistry List Conference Page at</em>
<a href="http://www.ccl.net/chemistry/a/conferences/"
class="link">http://www.ccl.net/chemistry/a/conferences/</a>.