From: chemistry-request at ccl.net <br />
To: chemistry-request at ccl.net<br />
Date: Mon Jan 22 10:41:27 2024<br />
Subject: 24.03.05 <span class="fancysmall">CUP XXIII: Annual Scientific Meeting to discuss the challenges in drug discovery by OpenEye, Cadence Molecular Sciences</span><br />

<pre>CUP XXIII - Santa Fe March 5-7, 2024

CUP is OpenEye, Cadence Molecular Sciences&#39; annual scientific meeting held at La Fonda on the Plaza in Santa Fe where we bring together top Scientists, Customers, Users, and Programmers in the industry to discuss the challenges in drug discovery.

Register here: <a href="https://www.eyesopen.com/events/cup-2024" target="_blank">https://www.eyesopen.com/events/cup-2024</a>

This year, in addition to a day of reports from OpenEye scientists, we will have two keynote speakers and four half-day sessions planned on the topics below:

Sessions:

*Cheating at large-scale - As virtual databases get larger and larger, how do we search such 3D chemical spaces efficiently?

*Next steps with Affinity - Although free-energy methods have made a significant impact, they aren&acirc;&#128;&#153;t as robust or accurate as we&acirc;&#128;&#153;d like.

*Structural Toxicology - As techniques such as cryoEM remove previous limits on what can be resolved, how much of ADME can we begin to model?

*Hype vs Hope&acirc;&#128;&#157; - Is the excitement around new techniques and technologies justified? Tell us of your experiences with LLMs, quantum computing, large-scale dynamics or any thing else that either lives up to its hype or doesn&acirc;&#128;&#153;t.

 
Keynote Speakers:

Charlotte Deane, Professor of Structural Bioinformatics at Oxford and Exscientia Chief AI Officer, will give the Levinthal lecture.

Christian Cortis, COO of Tectonic Therapeutic will give the Frank Brown Industry Perspective talk. Chris was a Board member of OpenEye, where he contributed his unique experiences of both the financial world and that of biotech.

 
Call for Presentations: Please submit your abstract for poster or oral presentations.</pre>
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