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Date: Fri, 23 Feb 2001 09:37:48 +0100
From: David Turner <dturner /at\syntem-sa.fr>
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Organization: Computational Drug Design, Syntem
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To: Computational Chemistry List <chemistry {*at*} ccl.net>
Subject: Protease Inhibitors Entropy/Enthalpy
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Hi

Can anybody point me to an article or articles discussing the
relative contributions of entropic and enthalpic terms to the
free energy of binding of substrates and/or inhibitors of HIV
protease or perhaps in more general terms for aspartic and the
various other classes of proteases? 

Thanks

Dave

-- 

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David Turner                                             Synt:em
Senior Modeling Scientist              Parc Scientifique G.Besse
Computational Drug Discovery                         30000 Nimes
email: dturner-: at :-syntem.com                                 France

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