From chemistry-request@ccl.net Fri Jun 14 19:14:42 1991 Date: Fri, 14 Jun 91 18:34:31 EST From: Shaun Black Subject: Poly-Ala To: "Peter Shenkin, et al." Status: R It is my recollection that poly-Ala is only sparingly soluble in water, but enough can be gotten into solution to do a CD spectrum and see that it is alpha helical. Poly-Gly will probably be more soluble in water, but only because it likely unfolds and hydrogen bonds with the solvent. My bet is for "random coil" in water. It's not clear to me what the entropic considerations would be, net. More discussion on this would be interesting. =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-= Shaun D. Black | Bitnet: black@ohstphrm.bitnet Ohio State University | Internet: black@ohstphrm.pharmacy.ohio-state.edu College of Pharmacy | Phone: (614) 292-3925 500 West 12th Avenue | FAX: (614) 292-2435 Columbus, OH 43210-1291 | :-) =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=