Problem with aggregates in SYBYL



Hello,
 Does SYBYL's MAXIMIN2 work with more than one aggregate?
 I minimized some RNA-hairpins with the stem defined as an aggregate (BIGAGG
 created with ANNEAL) and the results were satisfying.
 Sometimes though the loop-bases were twisted so I decided to fix them by
 defining them as aggregates (each one separately).
 After that I started MAXIMIN2. With some hairpins MAXIMIN2 survived 2-6
 iterations before giving the message: Line search Iteration limit reached.
 With another hairpin Sybyl crashed completely so I had to reboot my E&S
 PS350.
 Can somebody help me, please?
 Many thanks in advance
 				Peter Reinert