rational drug design

From: marty %-% at %-% ionchannel.med.harvard.edu (Marty Gallagher)
Subject: rational drug design
Date: Fri, 4 Feb 94 10:10:22 -0800

 Hello,
 	A while back someone asked about success stories in rational
 drug design.  In that light, what does the group think of the Merck
 groups article in *Science* 23:380-384 where they rationally designed
 inhibitors of HIV protease?
 -- Marty
 ========================================================================
 Martin J. Gallagher	    phone:   (617) 432-1729
 Dept. of Neurobiology	    fax:     (617) 734-7557
 Harvard Medical School	    E-mail:  marty %-% at %-% ionchannel.med.harvard.edu
 220 Longwood Ave
 Boston, MA  02115
 	Neither Schrodinger nor Einstein "suberted the dominant paradigm."
 Rather, they complemented it in order to descibe areas of the Ultimate
 Reality that Newton did not see.
 	Those who categorically reject tradition in order to avoid
 conformity are still bound by it. Those who seek truth for truth's sake
 are truly free.
 					-- Me