Experimental Hydrophobicities and partial charges



 Dear colleges,
 in our lab we are estimating the radius of biological ion channels by means
 of organic cations (for instance see David J. Adams, Terry M. Dwyer and
 Bertil Hille (1980). "The Permeability of Endplate Channels to Monovalent
 and Divalent Metal Cations." The Journal of General Physiology 75:
 493-510).
 To better understand the measurements it would be interesting if there are
 some experimental values for their hydrophobicities.
 Additionally, for model building studies I would like to know whether
 people did calculations on the partial charges on these molecules.
 The molecules are:
 NH4
 Methylamine
 Dimethylamine
 Trimethylamine
 Tetramethylamine
 Hydrazine                          (NH2)2-C-C(NH2)2
 Choline                            (Ch3)3-N-CH2-CH2-OH
 Tris-(hydroximethyl)-aminomethane  (CH2OH)3-N-CH3
 Thanks for your help in advance. I will compile a summary.
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 Eberhard von Kitzing
 Max-Planck-Institut fuer Medizische Forschung
 Jahnstr. 29, D69120 Heidelberg, FRG
 Carl-Zuckmayer Str. 17, D69126 Heidelberg (privat)
 FAX : +49-6221-486 459  (work)
 Tel.: +49-6221-486 467  (work)
 Tel.: +49-6221-385 129  (home)
 internet: vkitzing(-(at)-)sunny.MPImF-Heidelberg.mpg.de