Drug Design Seminar Serius

From: "Don Gregory" <Don_Gregory : at : MSI.COM>
Subject: Drug Design Seminar Serius
Date: 12 Jun 1994 12:18:51 +0000
                        Subject:                               Time:10:00 AM
   OFFICE MEMO          Drug Design Seminar Serius             Date:6/10/94
 Seminar Announcements!
 Announcing a free scientific seminar series presented by Molecular Simulations
 Inc. (MSI) and Hewlett Packard.  Speakers for this program will discuss
 innovative scientific methods for structure activity analysis  to enable users
 to increase the efficiency of the lead optimization and lead generation cycle
 in your organisation..  Topics will include:
 	o  Pharmacophore model generation
 	o  Database search strategies
 	o  Advanced QSAR techniques
 	o  Computer-aided compound selection
 	o  Molecular similarity
 	o  Pseudo-receptor model generation
 Coupling MSI's state-of-the-art modelling environment with the computational
 speed of Hewlett Packard's PA-RISC 7150 micro-processor, Hewlett Packard and
 MSI offer a complete solution that is fast, affordable, and easy to use.  The
 series 700 model 735 workstation with the 7150 microprocessor running on 125mhz
 with performance up to 154MIPS, is ideal for compute intensive and demanding
 graphics applications.
 To register for any of the following seminars, call Molecular Simulations Inc.
 at (617) 229-9800, extension 567 in the U.S.  In Europe, call +44 223 413302,
 extension 31.
 MOLECULAR SIMULATIONS INC. AND HEWLETT PACKARD PRESENT:
 STRATEGIES IN DRUG DISCOVERY SEMINAR SERIES IN THE U.S.
 Monday, July 18
 Cambridge, MA
 Tuesday, July 19
 New Brunswick, NJ
 Wednesday, July 20
 Research Triangle Park, NC
 Thursday, July 21
 La Jolla, CA
 Friday, July 22
 Burlingame, CA
 (San Francisco Airport area)
 THE AGENDA
 8:00am	       Registration and Continental Breakfast
 8:30am	      Introduction and Welcome
 8:45am        Dr. Anthony Hopfinger, University of Illinois
  	           	"Strategies for the Construction of
 	           	  3D QSARs Based upon Molecular
 	           	  Shape Analysis"
 9:30am        Dr. David Rogers, Molecular Simulations Inc.
 	             	"QSAR Analysis using Genetic Algorithms"
 10:15am     Product Demonstration
 10:30am       Coffee Break
 10:45am       Dr. Peter Sprague, BioCAD Corporation
 		               "Structure Activity Analysis with Catalyst:
 		                  Conversion of Peptide Lead Information into
                      Non-peptide Drug Candidates"
 11:30am        Dr. Simon Kearsley, Merck Research Laboratories
 	                	"Computer-Aided Compound Selection Techniques"
 12:15pm       Product Demonstration
 =================================
 STRATEGIES IN DRUG DISCOVERY SEMINAR SERIES IN EUROPE
 Tuesday, 28 June
 Stockholm, Sweden
 Wednesday, 29 June
 Paris, France
 Thursday, 30 June
 Frankfurt, Germany
 Friday, 1 July
 London, England
 AGENDA
 9:30am	       Registration and Coffee
 10:00am	      Introduction and Welcome
 10:15am       Dr. Anthony Hopfinger, University of Illinois
  	           	"Strategies for the Construction of
 	            	  3D QSARs Based upon Molecular
 		              Shape Analysis"
 11:00am        Dr. David Rogers, Molecular Simulations Inc.
 	               	"QSAR Analysis using Genetic Algorithms"
 11:45pm     Product Demonstration
 12:00pm       Lunch
 13:00pm       Dr. Peter Sprague, BioCAD Corporation
 		"Structure Activity Analysis with Catalyst:
 		  Conversion of Peptide Lead Information into
      Non-peptide Drug Candidates"
 14:00pm        Dr. Simon Kearsley, Merck Research Laboratories
 		"Computer-Aided Compound Selection Techniques"
 15:00pm        Product Demonstration
 THE SPEAKERS
 Dr. Anthony Hopfinger  -  Dr. Hopfinger is Professor of Medicinal Chemistry,
 Chemistry and Chemical Engineering at the University of Illinois at Chicago.
 He received  his Ph.D. from Case Western Reserve University, and was an NIH
 post-doctoral fellow at Harvard Medical School.  Following post-doctoral
 studies, Dr. Hopfinger was a member of the faculty at Case Western Reserve
 University.  In 1981 he joined G.D. Searle and Company as Director of Medicinal
 Chemistry, and in 1985 he took up his current position.   Professor Hopfinger
 has over 185 publications including three books, and is co-founder of three
 companies focused on computational chemistry software and biotechnology.
 Dr. Peter W. Sprague  -  Dr. Sprague was educated (BS, PhD) in synthetic
 organic chemistry at Case-Western Reserve University and held acadmic positions
 at Indiana Universityand California State University at San Bernardino.  He
 joined Bristol-Myers Squibb in 1972 and was involved with various medicinal
 chemistry projects including ACE inhibition and Thromboxane Antagonism until
 leaving in 1991 to join BioCAD Corporation where he currently holds the
 position of Vice President for Support.
 Dr. Simon Kearsley  -  Dr. Kearsley is currently  a Senior Research Fellow at
 Merck Research Laboratories in charge of developing scientific computing
 methodology relevant to drug design.  He earned his Ph.D. in Physical Chemistry
 from Cam-bridge University in England working with Professor Thomas.  Dr.
 Kearsley also did post-doctoral work at Yale University with Professors McBride
 and Prestegard.
 Dr. David Rogers  -  Dr. Rogers joined MSI in 1991, and is currently leading
 the development of several applications based upon Genetic Algorithms.  He
 earned his doctorate work-ing with Professor W. Todd Wipke at UC-Santa Cruz,
 followed by post-doctoral appointments at the MIT Artificial Intelligence Lab
 and the University of Michigan Cognitive Science Lab.  Dr. Rogers has since
 published on a wide range of topics, including compu-tational chemistry, neural
 networks, statistics, brain research, and genetic algorithms.
 To register for any of the following seminars, call Molecular Simulations Inc.
 at (617) 229-9800, extension 567 in the U.S.  In Europe, call +44 223 413302,
 extension 31.