More AMBER atom types

[Charles Letner <cletner()at()remcure.bmb.wright.edu>]

 Hello,
 	I just finished reading the summary of kd7()at()tower.york.ac.uk about
 atom types in AMBER.  It seems that this approach of taking a atom type
 from the AMBER force field and using this as an atom type in a non-protein
 molecule is OK.  However, I'm wondering how general this is.  I'm planning
 on including substrates in some of my upcoming MDs.  As these only contain
 C, H, N, and O,  I can probably find similar atoms among the standard atoms
 of AMBER.  So, is this reasonable or should I still think about creating
 new parameters (ala tha Hopfinger & Pearlstein, 1984 article)?  I'd be
 very interested in opinions as well as aspects that should be considered
 when making this decision.
 Thanks for your time,
 Chuck
 Charles Letner
 Wright State University
 Department of Biochemistry
 Dayton, OH 45435
 e-mail: cletner()at()remcure.bmb.wright.edu