Re: Look for Refs. of Rational Drug Design
Arthur Wang writes:
<I am looking for some references of rational drug design. Would you
<please give me some hints?
I have several references that may be of interest to you:
1.Electronic sources:
Lisa Balbes' Guide to Rational (Computer-Aided) Drug Design, February
1992; accesible via gopher to www.ccl.net (directory and file: Internet
file server (ftp) Sites/Chemistry/pub/chemistry/documents/drug.design.guide)
2.Books:
Burger, A. A guide to the chemical basis of drug design, John
Wiley & Sons: New York, 1983 300p
Coulson,C.J. Molecular mechanisms of drug action, Taylor & Francis:
London, 2nd ed., 1994 294p
Medicinal Chemistry: The role of organic chemistry in drug research,
Ganellin,C.R., Roberts,S.M.,Eds.; Academic Press, London, 2nd ed., 1993 302p
Goodman and Gilman's the pharmacological basis of therapeutics,
Gilman,A.G., et al., Eds., Pergamon: New York, 8th ed., 1990, 1811p
Comprehensive medicinal chemistry: the rational design, mechanistic
study & therapeutic applications of chemical compounds; Hansch,C.(chairman
of
the editorial board), Pergamon Press: Oxford, vol. 1-6, 1990
Conformation in biology and drug design, Hruby,V.J.,Ed., Academic:
Orlando, Fla., 1985 495p
The application of charge density research to chemistry and drug
design; Jeffrey,G.A.; Piniella,J.F.,Eds.; Plenum Press:New York, 1991 409p
Frontiers in drug research: crystallographic and computational methods;
Jensen,B., Joergensen,F.s., Kofod,H., Eds.; Munksgaard: Copenhagen, 1990 418p
A textbook of drug design and development, Krogsgaard-Larsen, P.;
Bundgaard, H., Eds.; Harwood Academic: Chur, 1991, 643p
Kubinyi,H. QSAR: Hansch analysis and related approaches; VCH: Weinheim,
1993 240p
Molecular design and modeling: Concepts and applications Part A
Proteins, peptides, and enzymes (Methods in enzymology Volume 202), Part B
Antibodies and antigens, nucleic acids, polysaccharides, and drugs (Methods in
enzymology Volume 203); Langone,J.J.,Ed; Academic Press, San Diego, 1991
824+764p
Martin, Y. Connolly Quantitative drug design: a critical introduction;
Marcel Dekker: New York, 1978, 425p
Martin, Y. Connolly; Kutter,E.; Austel,V. Modern drug research: paths
to better and safer drugs, Dekker:New York, 1989 507p
Computer-Aided Drug Design. Methods and Applications, Perun, T.J.,
Propst, C.L., Eds.; Marcel Dekker: New York, 1989 493p
Medications development: drug discovery, databases, and computer-aided
drug design, Rapaka,R.S., Hawks,R.L., Eds.; National Institute on Drug Abuse:
Rockville,MD, 1993 288p
Bioreversible carriers in drug design: theory and applications, Roche,
E.B., Ed.; Pergamon: New York, 1987 292p
Silverman, R.B. The organic chemistry of drug design and drug action;
Academic: San Diego, 1992 422p
Smith,H.J. Smith and Williams' introduction to the principles of drug
design, Wright: London, 2nd ed., 1988 333p
3.Articles:
Bugg,C.E.; Carson,W.M.; Montgomery,J.A. Drugs by design, Scientific
American, 1993, 92-98.
Kuntz,I.D. Structure-Based Strategies for Drug Design and Discovery,
Science 1992, 257, 1078-1082.
Kuntz,I.D.; Meng,E.C.; Shoichet,B.K. Structure-Based Molecular Design,
Acc. Chem. Res. 1994, 27, 117-123.
Verlinde,C.L.M.J.; Hol, W.G.J. Structure-based drug design: progress,
results, and challenges, Structure 1994, 2, 577-587.
Also, Dr. David A. Winkler posted quite a while ago a summary on success
stories in molecular design.
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Dan Fercu | E-mail (Internet):
Computational Chemist | fercu (+ at +)
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Department of Chemistry | dxf11 (+ at +) po.cwru.edu
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