QSAR - Followup, again



 Hi all,
   Thanks again for all of your responses. I will post a summary in a
 couple
 of days when the discussion is over. All of the responses I've received
 so
 far have come to CCL and not to my personal mailbox, but if it is
 desired,
 I can still post a compilation of the responses.
   I forgot to mention 2 very important facts:
    1) I am using SYBYL and have no access to anything else, save the
        free software on the net. I cannot use that however, for the
 second
        reason.
    2) My mentor insists that I do the overlays by hand, that is, by
 using
        the fit module in SYBYL and picking points, with the mouse, to
 fit.
        I must also do torsion adjustments by hand, that is, by choosing
        a torsion angle for each bond and applying it, using either the
 twist
        widget in the upper left corner of the screen or the modify
 torsion
        command.
                                            Susan