Summary: charges from X-ray



 Yesterday, I sent the following:
      All,
      I was wondering if anyone knows of any work, etc. in
      extracting
      quantities such as partially atomic charges, etc. from
      experimental
      densities obtained by small molecule crystallography.  Also,
      if
      anyone knows of any X-ray programs that do this or of any
      utilities
      that extract information such as ESP's, etc., from the x-ray
      data that
      can be passed into a standard QC code.
      Thanks in advance, Bill
      P.S. I know such quantities as partial atomic charges are not
      uniquely
      defined, but, analogously to QC, for a given definition useful
      trends,
      etc. may be deduced.
 Here are the responses so far:
 _____________________________________________________________________
 Subject: Re: CCL:charges fro X-ray
    Date: Thu, 3 Sep 1998 15:30:48 -0500 (CDT)
    From: Nathalie Godbout <godbout-: at :-chad.scs.uiuc.edu>
      To: Bill Laidig <laidig-: at :-pandora.na.pg.com>
   Hi Bill,
     We have been using XD- A Computer Program Package for Mulitpole
 Refinement and Analysis of Electron Densities from Diffraction Data,
 Koritsanszky, T.; Howard, S.; Richter, T.; Su, Z.; Mallison, P. R.;
 Hansen, N. K. Free University of Berlin
     They have a web site. You can get information about how
 to get the program from them.
    Nathalie
  --------------------------------------------
 | Nathalie Godbout                           |
 | University of Illinois at Urbana-Champaign |
 | 600 S. Goodwin Av. Box 23.6                |
 | Urbana, IL 61801                           |
  --------------------------------------------
 _____________________________________________________________________
      Subject: Re: CCL:charges fro X-ray
         Date: Thu, 03 Sep 1998 17:52:32 -0400
         From: Jim Gano <jgano-: at :-uoft02.utoledo.edu>
 Organization: Instrumentation Center in Arts and Sciences -: at :- the
 University of Toledo
           To: Bill Laidig <laidig-: at :-pandora.na.pg.com>, apinker-: at
 :-uoft02.utoledo.edu
   References:
             1
 Bill,
 I have forwarded your request to my colleague Alan Pinkerton who is an expert in
 this area.  Our activities at our crystallography facility routinely involve
 experimental determination of electron densities.
 Jim--
 James E. Gano, Director ->http://www.chem.utoledo.edu/chem/FAC_INFO/jgano.html
 Instrumentation Center in Arts & Sciences ->http://www.icenter.utoledo.edu
 Home of the Ohio Crystallography Consortium
 ->http://www.icenter.utoledo.edu/icenter/occ.htmlx
 200 Bowman-Oddy Laboratories
 University of Toledo -> http://www.utoledo.edu
 Toledo, Ohio 43606 U.S.A.
 Phone: 419-530-7847
 FAX: 419-530-4033
 E-mail:  icenter-: at :-uoft02.utoledo.edu
 _____________________________________________________________________
 Subject: RE: CCL:charges from X-ray Data
    Date: Thu, 3 Sep 1998 18:16:22 MDT
    From: mcarducci-: at :-xray0.chem.arizona.edu
      To: chemistry-: at :-www.ccl.net, laidig-: at :-pandora.na.pg.com
 Bill Laidig (and other interested parties),
 There is a lively community of scientists studying atomic charges (and other
 properties) derived from experimentally determined charge densities by small
 molecule X-ray diffraction. I have appended below an "Introduction to
 Charge
 Density Literature" that will give you lots of good starting points. I
 picked
 them to emphasize the experimental side of things, but theory gets a good
 coverage too. That question about defining a charge partitioning scheme is a
 tough one. Lecomte has the only group that I am aware of that is working on
 using derived charges in quantum mechanical programs, though I am sure there
 are others.
 As for the software used in these experiments, the most up-to-date, complete
 and widely used package available is XD. You can find more information about
 it at http://www.chem.gla.ac.uk/~paul/xd.html. The XDPROP portion
 I hope this helps you out,
                         ---Michael Carducci
                         Molecular Structure Laboratory
                         Department of Chemistry
                         University of Arizona
                         Tucson, AZ 85721 USA
                         Email: carducci-: at :-u.arizona.edu
                         Phone: (520)621-4168
                         Fax  : (520)621-8407
 <-------------------------------------------------------------------------->
                   Introduction to Charge Density Literature
 X-ray Charge Densities and Chemical Bonding by Philip Coppens IUCR Book Series,
 Oxfor
 University Press 1997
 The Application of Charge Density Research to Chemistry and Drug Design Edited
 by George
 Jeffrey and Juan Piniella NATO ASI Series B Volume#250 Plenum Press 1991
 Studies of Electron Distributions in Molecules and Crystals Edited by Robert
 Blessing
 Transactions of the ACA Vol.#26 1990
 Electron Density from X-Ray Diffraction by P. Coppens Annu. Rev. Phys. Chem.
 1992. 43:663-
 692
 Chasing the Elusive d Electron with X-rays by Philip Coppens Chapter 4 in
 Computational
 Chemistry: The challenge of d and f electrons; Salahub, D.R.; Zerner,M.C.,
 Editors;ACS
 Symposium Series No.394 1989
 Israel Journal of Chemistry (entire Symposium Issue) Vol.16 1977
 Papers on Individual Compounds can be found by searches with the following
 authors (I just pulled out a few papers from my files):
 P.R. Mallinson, et. al. J. Chem. Phy. 97(8), 15 Oct. 1992
 T. Koritsanszky, et al. JACS 1991, 113,9148-9154
 C. Lecomte, et.al. Acta Cryst. (1991) B47, 253-266
 B. Craven, et.al. Acta Cryst. (1984). B40, 511-518
 Yu Wang, et.al. Acta Cryst. (1992). B48, 319-324
 _____________________________________________________________________
 Subject: Re: CCL:charges fro X-ray
    Date: Fri, 4 Sep 1998 08:24:25 +0200 (DFT)
    From: assfeld-: at :-host23.lctn.u-nancy.fr
      To: laidig-: at :-pandora.na.pg.com
 Hi,
 have a look at the work of LECOMTE (Claude)
 from the
 "Laboratoire de Cristallographie et de Modelisation
 des Materiaux Mineraux et Biologiques."
 Faculte des Sciences, BP 239
 Universite Henri Poincare
 F-54506 Vandoeuvre-les-Nancy, France
 Hope this helps.
                                       ...Xav
 Xavier Assfeld                      assfeld-: at :-lctn.u-nancy.fr
 Laboratoire de Chimie theorique     (T) 33 3 83 91 21 49
 Universite Henri Poincare           (F) 33 3 83 91 25 30
 F-54506 Nancy BP 239
 _____________________________________________________________________
      Subject: Re: CCL:charges fro X-ray
         Date: Fri, 04 Sep 1998 12:55:33 -0300
         From: Anselmo Elcana de Oliveira <elcana-: at :-iqm.unicamp.br>
 Organization: IQ - UNICAMP
           To: Bill Laidig <laidig-: at :-pandora.na.pg.com>
 Hi Bill,
  give a glance in those references:
 - Guadagnini, P.H., Oliveira, A.E. e Bruns, R.E.,
 ?Core Electron Energies, Infrared Intensities, and Atomic Charges? J. Am. Chem.
 Soc. 1997, 119, 4224.
 - de Oliveira, A.E., Guadagnini, P.H., Custódio, R. e Bruns, R.E.
 ?Infrared Vibrational Intensities, Polar Tensors and Core Electron Binding
 Energies of the Group IV Hydrides and the Fluorosilanes?, J. Phys. Chem. A 1998,
 102, 4615.
 Anselmo Elcana
 _____________________________________________________________________
 Subject: Re: CCL:charges fro X-ray
    Date: Fri, 4 Sep 1998 10:00:03 -0700 (PDT)
    From: ross-: at :-cgl.ucsf.edu
      To: laidig-: at :-pandora.na.pg.com
 Look for work by Pearlman & Kim.
 Bill Ross
 _____________________________________________________________________
 Subject: charges from xray structures
    Date: Fri, 4 Sep 1998 13:41:34 EDT
    From: wrw45-: at :-aol.com
      To: laidig-: at :-pandora.na.pg.com
 Dear Bill:
  ...personal note deleted...
 But to get to your question, I know that Al Cotton's groups at A&M has done
 some of this.  They get high quality structures at low temperatures and try to
 extract charge data.  I don't have anything handy, but you might search Al's
 publications and come up with something.
 hope this is helpful
 Randy Winchester
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