Subject: Protease Inhibitors Entropy/Enthalpy

From: David Turner <[email-masked]>
Date: Fri, 23 Feb 2001 09:37:48 +0100

Hi

Can anybody point me to an article or articles discussing the
relative contributions of entropic and enthalpic terms to the
free energy of binding of substrates and/or inhibitors of HIV
protease or perhaps in more general terms for aspartic and the
various other classes of proteases? 

Thanks

Dave

-- 

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David Turner                                             Synt:em
Senior Modeling Scientist              Parc Scientifique G.Besse
Computational Drug Discovery                         30000 Nimes
email: [email-masked]                                 France

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