software to measure the "size" (area) of a substrate binding poc ket

From: "Bienstock.Rachelle" <biensto1 { *at * } niehs.nih.gov>
Subject: software to measure the "size" (area) of a substrate binding poc ket
Date: Thu, 11 Oct 2001 17:11:49 -0400

 HI CCL Folks:
 Can anyone recommend some good, (free), easy to use software to
 quantify the size of a substrate
 binding pocket, so that the size of this pocket can be compared
 between 2 enzymes?  (for example
 a mutant and wild type)?
 Any advice greatly appreciated!
 Thanks,
 Rachelle
 Dr. Rachelle J. Bienstock
 Molecular Modeling and Structural Biochemistry
 NIH
 NIEHS / ITSS
 P.O. Box 12233 MD F0-011
 Research Triangle Park, NC 27709
 Telephone: (919) 541-3397   Fax: (919) 541-5737
 E-mail: biensto1 { *at * } niehs.nih.gov
 Office: Room F091