From chemistry-request@server.ccl.net Fri Jul 12 15:58:50 2002 Received: from mail.csusb.edu ([139.182.2.16]) by server.ccl.net (8.11.6/8.11.0) with ESMTP id g6CJwor02798 for ; Fri, 12 Jul 2002 15:58:50 -0400 Received: from mail.csusb.edu (localhost [127.0.0.1]) by mail.csusb.edu (8.12.5/8.12.5) with ESMTP id g6CJvD5j015421; Fri, 12 Jul 2002 12:57:13 -0700 (PDT) Received: from localhost (kcousins@localhost) by mail.csusb.edu (8.12.5/8.12.5/Submit) with SMTP id g6CJvCgc015413; Fri, 12 Jul 2002 12:57:12 -0700 (PDT) Date: Fri, 12 Jul 2002 12:57:12 -0700 (PDT) From: Kimberley Cousins To: "Dr. Sudhir A. Kulkarni" cc: chemistry@ccl.net Subject: Re: CCL:QSAR equation In-Reply-To: <3D2EE104.EA62E56F@mahindrabt.com> Message-ID: MIME-Version: 1.0 Content-Type: TEXT/PLAIN; charset=US-ASCII I was just reading a review that addresses this, in 'Reviews in Computational Chemistry" volume 11. See http://chem.iupui.edu/~boyd/rcc.html Kimberley Cousins Associate Professor of Chemistry California State University, San Bernardino 5500 University Parkway San Bernardino, CA 92407 (909)880-5391 kcousins@csusb.edu http://chem.csusb.edu/~kcousins On Fri, 12 Jul 2002, Dr. Sudhir A. Kulkarni wrote: > Hi, > I was wondering about one thing which could be a simple query for > many of you. > What is the significance of cross correlation of independent terms in a > QSAR equation generated using multiple regression? > If I have a QSAR equation with high cross correlation of independent > terms but the prediction of test compounds are good, should I consider > this equation seriously? > Any suggestion or literature reference on this would be highly > appreciated. > Thanks. > > Sudhir > > ********************************************************* > Disclaimer > > This message (including any attachments) contains > confidential information intended for a specific > individual and purpose, and is protected by law. > If you are not the intended recipient, you should > delete this message and are hereby notified that > any disclosure, copying, or distribution of this > message, or the taking of any action based on it, > is strictly prohibited. > > ********************************************************* > Visit us at http://www.mahindrabt.com