From owner-chemistry@ccl.net Tue Jun 5 15:50:01 2007 From: "Peter Rose prose001###san.rr.com" To: CCL Subject: CCL: Any computational method to predict binding affinities of metals for different PROTEINS? Message-Id: <-34420-070605152810-9145-uBzmZ/PfiyWeJUxBjZFh3w-.-server.ccl.net> X-Original-From: "Peter Rose" Content-Type: multipart/alternative; boundary="----=_NextPart_000_0022_01C7A752.BFB3FFB0" Date: Tue, 5 Jun 2007 09:20:23 -0700 MIME-Version: 1.0 Sent to CCL by: "Peter Rose" [prose001%%san.rr.com] This is a multi-part message in MIME format. ------=_NextPart_000_0022_01C7A752.BFB3FFB0 Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 7bit Here are a couple of recent papers that identify metal binding motifs on a qualitative basis: Richard Thilakaraj , Krishnan Raghunathan , Sharmila Anishetty, and Gautam Pennathur, In silico identification of putative metal binding motifs, Bioinformatics 2007 23(3):267-271. Passerini A, Andreini C, Menchetti S, Rosato A, Frasconi P., Predicting zinc binding at the proteome level, BMC Bioinformatics 2007 Feb 5, 8-39 The software implementing the predictor is freely available at: http://zincfinder.dsi.unifi.it Peter Rose, Ph.D. InSilicoChem, Inc. _____ > From: owner-chemistry---ccl.net [mailto:owner-chemistry---ccl.net] Sent: Tuesday, June 05, 2007 12:39 AM To: Rose, Peter W Subject: CCL: Any computational method to predict binding affinities of metals for different PROTEINS? Dear CCL list members, I wonder if there is any computational method that I can use to predict if when adding Zn2+ to a solution that contains the same concentration of two different proteins, the ions will bind, preferably, to one of the two proteins. With many thanks in advances Yours sincerely, Gerard ------=_NextPart_000_0022_01C7A752.BFB3FFB0 Content-Type: text/html; charset="us-ascii" Content-Transfer-Encoding: quoted-printable

Here are a couple of recent papers = that identify metal binding motifs on a qualitative = basis:

 

=

Richard Thilakaraj , Krishnan = Raghunathan , Sharmila Anishetty, and Gautam Pennathur, =

In silico identification of = putative metal binding motifs, Bioinformatics 2007 23(3):267-271.

 

=

Passerini A, = Andreini C, Menchetti S, Rosato A, Frasconi P.,

Predicting zinc = binding at the proteome level, BMC Bioinformatics 2007 Feb 5, 8-39

The software implementing the = predictor is freely available at: = http://zincfinder.dsi.unifi.it

 

=

Peter Rose, = Ph.D.

InSilicoChem, = Inc.

 

From: owner-chemistry---ccl.net [mailto:owner-chemistry---ccl.net]
Sent: Tuesday, June 05, = 2007 12:39 AM
To: Rose, Peter W =
Subject: CCL: Any = computational method to predict binding affinities of metals for different = PROTEINS?

 




Dear CCL list members,

I wonder if there is any computational method that I can use to predict = if when adding Zn2+ to a solution that contains the same concentration of two = different proteins, the ions will bind, preferably, to one of the two proteins. =

With many thanks in advances

Yours sincerely,

Gerard

------=_NextPart_000_0022_01C7A752.BFB3FFB0--