CCL:G: QM/MM question



Dear CCL'ers:

I would like to perform some QM/MM calculations but I don't seem to be able to find adequate software for it that is free for academic use. Are the choices really so limited? So far, I am aware of GAMESS interfaced to a very dated version of Tinker and then QMMM software from Dr. Truhlar's lab that is able to use also GAMESS and Tinker albeit in a limited way because of limitations in GAMESS.

I have no money to pay for Gaussian or Schrodinger's Qsite and I sort of refuse to pay 500 UK Pounds for Chemshell on the basis that I am not British (not to mention that most of the software they use as a base for theirs is free and/or developed elsewhere).

Anyway, I would appreciate any insights into what choices I have for  QM/MM software that would allow me to do calculations like geometry optimizations, transition states, etc. in protein systems. Thanks for the help!

Maurizzio