From owner-chemistry@ccl.net Sat Jan 15 16:33:00 2011
From: "Andrew Voronkov drugdesign[]yandex.ru" <owner-chemistry:-:server.ccl.net>
To: CCL
Subject: CCL: in silico biotargets fishing - reverse screening
Message-Id: <-43643-110114062438-16466-JaeDcNazwnQopK4mHFx0Pw:-:server.ccl.net>
X-Original-From: Andrew Voronkov <drugdesign{}yandex.ru>
Content-Transfer-Encoding: 7bit
Content-Type: text/plain
Date: Fri, 14 Jan 2011 14:24:23 +0300
MIME-Version: 1.0


Sent to CCL by: Andrew Voronkov [drugdesign+*+yandex.ru]
Dear CCL users, 
I have seen a very interesting presentation from Intelligand on biotargets in silico deconvolution for the known compounds. This is pharmacophore-based screening approach for some sets of biotargets. What are other methods, software and approaches available for in silico biotarget identification for compounds without know targets-mechanisms of action? The best of course would be to find some tools which is possible to use locally?


Best regards,
Andrew