CCL: Nitrenium ion on the Guanosine base

[Sergio Manzetti <sergio.manzetti:_:gmail.com>]

 Dear CCLrs, I am running some calculations on benzo[a]pyrene and its qualities,
 but they do not seem to be familiar with other carcinogens, although this is one
 of the most potent carcinogens. The mechanism of adduct formation is delineated
 in the literature as a amine-epoxy mechanism, but some issues do not compare
 well to this theory. Has anyone one this list seen a reference or thought about
 that the guanosine base may undergo ceonversion to a nitrenium-guanosine upon
 interaction with the epoxide or a radical of the PAH?
 
Best wishes

Sergio