From owner-chemistry@ccl.net Wed Mar 21 14:41:00 2012 From: "James Gary Prudhomme jprudhomme!^!healthtech.com" To: CCL Subject: CCL: First Principles in Binding Kinetics Message-Id: <-46539-120321122600-1723-/kftxhU/CjB0ACoR5KYaOQ]*[server.ccl.net> X-Original-From: "James Gary Prudhomme" Date: Wed, 21 Mar 2012 12:25:58 -0400 Sent to CCL by: "James Gary Prudhomme" [jprudhomme . healthtech.com] ***Please distribute this message to your colleagues. Thank you.*** Dinner Short Course Announcement: First Principles in Binding Kinetics:Towards Predicting Structure-Kinetics Relationships* June 6, 2012 - 6:00-8:00 pm Royal Sonesta Hotel Boston, Cambridge, Massachusetts Instructors: David Swinney, Ph.D., CEO, Institute for Rare and Neglected Diseases Drug Discovery (iRND3) Xavier Barril, Ph.D., ICREA Research Professor, Physical Chemistry Department, University of Barcelona This course will address the questions on why should I care about kinetics and how can I understand and predict Structure-Kinetics relationships? We will first review the role of binding kinetics in drug action and then focus on the particular case of protein-ligand non-covalent complexes, reviewing what is known so far about the structural determinants of binding kinetics. This course will help you with a better understanding and increased awareness of current state of the chemistry and pharmacology of binding kinetics. This course is scheduled at the conclusion of Day One of CHI's co- located "Structure-Based Drug Design" conference. More details and to register: http://www.healthtech.com/sbd For questions or to register for this course and/or conference via telephone, call 781-972-5400.